Abstract: Hemangioma of the thyroid gland is a rare diagnosis and less than 35 cases have been previously published in literature. The pathogenesis unknown but it suggested to be developmental anomaly which associated with an incapability angioblastic mesenchyma form canals. On microscopic examination, should distinguished from reactive endothelial hyperplasia, angiosarcoma or hemangiosarcoma. ...

BACKGROUND Enhanced external counterpulsation (EECP) is a circulation assist device that may improve endothelial dysfunction by increasing shear stress. Chronic exposure of vascular endothelial cells and vascular smooth muscle cells to relatively high physiological shear stress has antiproliferative and vasoprotective effects. The present study hypothesizes that EECP inhibits intimal hyperplasi...

Hyperlipidemia may increase endothelial damage and promote accelerated atherogenesis in graft coronary vasculopathy. To study the effects of hypercholesterolemia on coronary endothelial dysfunction, intimal hyperplasia, and lipid content, a porcine model of heterotopic heart transplantation, allowing nonacute rejection without immunosuppressive drugs, was used. A high cholesterol diet was fed t...

Intravascular papillary endothelial hyperplasia (Masson's hemangioma) is a disease characterized by exuberant endothelial proliferation within the lumen of medium-sized veins. In 1923, Masson regarded this disease as a neoplasm inducing endothelial proliferation, however, now it is considered to be a reactive vascular proliferation following traumatic vascular stasis. The lesion has a propensit...

Intravascular papillary endothelial hyperplasia (intravascular angiomatosis) is a lesion which several authors regard as a reactive phenomenon associated with such vascular alterations as hemangiomas, hematomas, varix, thrombi or dilated vessels while others consider it a neoplasm. An extensive review of the literature and a discussion of the previously reported points of view with a report of ...

OBJECTIVE Vascular adventitial Sca1+ (stem cell antigen-1) progenitor cells preferentially differentiate into smooth muscle cells, which contribute to vascular remodeling and neointima formation in vessel grafts. Therefore, directing the differentiation of Sca1+ cells toward the endothelial lineage could represent a new therapeutic strategy against vascular disease. APPROACH AND RESULTS We th...

OBJECTIVE Vascular tumors of the conjunctiva in the horse are rare. We present a unique case of an intravascular papillary endothelial hyperplasia of the conjunctiva. ANIMAL STUDIED Horse. PROCEDURES Case report. A 6-year-old-mare presented with a red mass in the conjunctiva of the left eye. After complete ophthalmologic examination the lesion was excised. The tissue was processed for light...

Intravascular papillary endothelial hyperplasia is a benign nonneoplastic vascular lesion that consists of endothelial cells with abundant vascular tissue with papillary proliferation. An adult female had a painless growing dark red nodule on the left side of the lower lip and often touched and gnawed at it for more than 4 years. The lesion was a tender, smooth mass approximately 1 cm in diamet...

In 1923 Masson described a neo-plastic process consisting of papillary hyperplasia of the vascular endothelial cells, with a consequent obliteration of the vascular lumen, followed by degenerative changes. He introduced the term ‘vegetant intravascular hemangioendothelioma’. However, these days it is more commonly known as papillary endothelial hyperplasia (PEH) [1]. Although relatively rare, t...

OBJECTIVE Clusterin is induced in vascular smooth muscle cells (VSMCs) during atherosclerosis and injury-induced neointimal hyperplasia. However, its functional roles in VSMCs and endothelial cells remain controversial and elusive. This study was undertaken to clarify the role of clusterin in neointimal hyperplasia and elucidate its mechanism of action. METHODS AND RESULTS Adenovirus-mediated...