Introduction High-field magnetic resonance spectroscopy (MRS) has the potential to provide enhanced neurochemical information based on increased sensitivity and higher spectral resolution. However, problems arising in high-field magnetic resonance imaging (MRI), such as more pronounced B0 and B1 inhomogeneities, may decrease spectral resolution and ultimately the quantification accuracy. A mult...

The HL-LHC upgrade will use deflecting (or crab) cavities to compensate for geometric luminosity loss at low *  and non-zero crossing angle. A local scheme with crab cavity pairs across the IPs is used employing compact crab cavities at 400 MHz. Design of the cavities, the cryomodules and the RF system is well advanced. The LHC crab cavities will be validated initially with proton beam in the ...

the aim of this work is to evaluate the influence of fabrication methods on the com-pressive properties of sandwich composites using both experimental work and numerical simulations. two types of sandwich composites with e-glass/kevlar/polyester resin facings and end-grain balsa wood as core have been produced by vacuum infusion processing (vip) and hand-lay up (hl) method. compression tests on...

The relationship between calcium ions and the differentiation of human promyelocytic leukemia HL-60 cells was investigated. Proliferation of HL-60 cells incubated in calcium-free medium was inhibited without cell differentiation. On the other hand, incubation with 100 microM verapamil markedly inhibited cell proliferation and caused slight cell differentiation into monocytes. Both calcium-free ...

When incubated with N6-2'-O-dibutyryladenosine 3',5'-cyclic monophosphate (dbcAMP), HL-60 cells expressed formyl peptide receptor (FPR) (as assessed by ligand binding) and FPR transcripts in a time- and concentration-dependent fashion. Experiments using dbcAMP analogs modified at either the C-6 or C-8 position indicated that the process was mediated by a protein kinase A type I, and protein kin...

The A and J series of prostaglandins (PGs) accumulate in the nuclei to suppress the proliferation of cancer cells. Here we report that Delta7-PGA1 methyl ester, a synthetic anti-cancer PG, increased the level of mRNA for the cyclin-dependent kinase inhibitor p21 in human leukaemia HL-60 cells. The induction of p21 was associated with the accumulation of hypophosphorylated retinoblastoma protein...