To describe our initial experience and early outcomes with distal placement of the Neuron 6F guiding catheter through coiled ICA for aneurysmal EVT. We examined the utility of the Neuronf 70 6F guiding catheter for the embolization procedure in such cases, fourteen cases of aneurysm with coiling of the parent ICA are presented via traditional guiding catheters. With the support of 8F ENVOY guid...

A perforated-patch whole-cell recording method was used to determine whether nitric oxide signaling participates in acetylcholine (ACh)-induced regulation of basal L-type Ca2+ current (ICa,L) in cat atrial myocytes. Exposure to 1 microM ACh for 2 min inhibited basal ICa,L (-21 +/- 3%), and withdrawal of ACh elicited rebound stimulation of ICa,L above control (80 +/- 13%) (n = 23). Stimulation o...

PURPOSE To prospectively determine, for both digital subtraction angiography (DSA) and contrast material-enhanced magnetic resonance (MR) angiography, the accuracy of subjective visual impression (SVI) in the evaluation of internal carotid artery (ICA) stenosis, with objective caliper measurements serving as the reference standard. MATERIALS AND METHODS Local ethics committee approval and wri...

Introduction: The accuracy of analyzing Functional MRI (fMRI) data is usually decreases in the presence of noise and artifact sources. A common solution in for analyzing fMRI data having high noise is to use suitable preprocessing methods with the aim of data denoising. Some effects of preprocessing methods on the parametric methods such as general linear model (GLM) have previously been evalua...

To analyze EEG accurately, it is necessary to remove artifacts from EEG, which gets coupled with signal at the time of recording and can’t be eliminated at preprocessing stage. Ocular artifact is most obvious artifact in EEG. In this paper, a new method using Stationary Wavelet Enhanced Independent Component Analysis with a novel thresholding, is proposed for ocular artifact removal from EEG. P...

Background—Although downregulation of L-type Ca current (ICa,L) in chronic atrial fibrillation (AF) is an important determinant of electrical remodeling, the molecular mechanisms are not fully understood. Here, we tested whether reduced ICa,L in AF is associated with alterations in phosphorylation-dependent channel regulation. Methods and Results—We used whole-cell voltage-clamp technique and b...

BACKGROUND & OBJECTIVES All colonizing and invasive staphylococcal isolates may not produce biofilm but may turn biofilm producers in certain situations due to change in environmental factors. This study was done to test the hypothesis that non biofilm producing clinical staphylococci isolates turn biofilm producers in presence of sodium chloride (isotonic) and high concentration of glucose, ir...

This study investigated the effect of Icariin (ICA) supplementation on diabetic retinopathy (DR) in a streptozotocin-induced diabetic rat model system. Fifty Sprague Dawley rats were randomly distributed into a control group and a streptozotocin-induced diabetes group. Diabetic rats were randomly divided into two groups; one group received ICA 5 mg/kg/day for 12 weeks by oral gavage; the other ...

Introduction Independent Components Analysis (ICA) uses mutual information to reduce an fMRI dataset to a small group of source timecourses and corresponding localization maps. Resting state network (RSN) activity can then be distinguished from noise sources based on gray matter localization and temporal smoothness. In practice, components frequently have equivocal localization and mixed freque...