Annotation enrichment analysis of a gene list helps biologists to identify the potential biological functions associated with it. With the extensions of plant ontology categories, the discovery of significant ontology terms associated with a gene list becomes more and more informative. We introduce a tool to help biologists to find out these terms based on the expanding ontology database of the...

Detecting associations between an input gene set and annotated gene sets (e.g., pathways) is an important problem in modern molecular biology. In this paper, we propose two algorithms, termed NetPEA and NetPEA', for conducting network-based pathway enrichment analysis. Our algorithms consider not only shared genes but also gene-gene interactions. Both algorithms utilize a protein-protein intera...

heavy metals in the surface sediments of the two coastal ecosystems of cochin, southwest india were assessed. the study intends to evaluate the degree of anthropogenic influence on heavy metal concentration in the sediments of the mangrove and adjacent estuarine stations using enrichment factor and geoaccumulation index. the inverse relationship of cd and zn with texture in the mangrove sedimen...

Abstract Glycation is a spontaneous post-translational modification of lysine, arginine, and the N-terminus proteins. Protein glycation closely related to pathogenesis human diseases, including diabetes, Alzheimer’s disease, renal cancer. The levels advanced end products (AGEs) are positively correlated with progression many diseases. However, it remains challenging analyze glycation-related pr...