We examined memory performance and cortical source localization of old/new effects in a source memory task in obsessive-compulsive disorder (OCD) patients by employing an equivalent current dipole (ECD) model using EEG and a realistic head model. Event-related potentials (ERPs) were recorded while 14 OCD patients and 14 age-, sex-, handedness-, and educational level-matched healthy control subj...

BACKGROUND Traditionally, tinnitus accompanied by hemifacial spasm has been considered a type of hyperactive neurovascular compression syndrome that is similar to hemifacial spasm alone because of the anatomically close relationship between the facial nerve and cochlear nerve as well as the hyperactive clinical nature. METHODS Participants were 29 subjects who presented with hemifacial spasm ...

Slow acoustic modulations below 20 Hz, of varying bandwidths, are dominant components of speech and many other natural sounds. The dynamic neural representations of these modulations are difficult to study through noninvasive neural-recording methods, however, because of the omnipresent background of slow neural oscillations throughout the brain. We recorded the auditory steady-state responses ...

The detailed time courses of cortical activities and source localizations following passive finger movement were studied using whole-head magnetoencephalography (MEG). We recorded motor-related cortical magnetic fields following voluntary movement and somatosensory-evoked magnetic fields following passive movement (PM) in 13 volunteers. The most prominent movement-evoked magnetic field (MEF1) f...

Magnetoencephalography (MEG) allows millisecond-scale non-invasive measurement of magnetic fields generated by neural currents in the brain. However, localization of the underlying current sources is ambiguous due to the so-called inverse problem. The most widely used source localization methods (i.e., minimum-norm and minimum-current estimates (MNE and MCE) and equivalent current dipole (ECD) ...

We develop a novel approach of cross-modal correspondence analysis (CMCA) to address whether brain activities observed in magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) represent a common neuronal subpopulation, and if so, which frequency band obtained by MEG best fits the common brain areas. Fourteen adults were investigated by whole-head MEG using a single equiv...

OBJECTIVE Medical intractable epilepsy is a common condition that affects 40% of epileptic patients that generally have to undergo resective surgery. Magnetoencephalography (MEG) has been increasingly used to identify the epileptogenic foci through equivalent current dipole (ECD) modeling, one of the most accepted methods to obtain an accurate localization of interictal epileptiform discharges ...

We survey the field of magnetoencephalography (MEG) and electroencephalography (EEG) source estimation. These modalities offer the potential for functional brain mapping with temporal resolution in the millisecond range. However, the limited number of spatial measurements and the ill-posedness of the inverse problem present significant limits to our ability to produce accurate spatial maps from...

The purpose of this study was to examine the spatial and temporal relationship between bilateral foci of bilaterally synchronous discharges in benign rolandic epilepsy of childhood (BREC) using a whole-scalp neuromagnetometer. We simultaneously recorded interictal magnetoencephalographic (MEG) and electroencephalographic (EEG) signals in six children with BREC. Interictal spikes were classified...