Background: Systemic Lupus Erythematosus is a kind of multi-system autoimmune disorder with unknown aetiology and it produces antibodies against various tissues. Case Presentation:The patient wasa 44-year-old woman with a history of Systemic Lupus Erythematosus for approximately five years, along with underlying diseases including peptic ulcers, asthma, h...

Systemic lupus erythematosus is a multi-system inflammatory disease. The clinical manifestations are diverse. Hepatic manifestation is a rarely seen complication of systemic lupus erythematosus. We report a case of complication of systemic lupus erythematosus presenting as cholestatic hepatitis in a 56-year-old Chinese woman. The cholestatic hepatitis progressed as part of the lupus activity an...

this case report demonstrates fatal gastrointestinal vasculitis as a rare presentation of systemic lupus erythematosus. a 34-year-old woman presented with abdominal pain and diarrhea. anti nuclear antibody was positive and high titre of anti-ds dna antibody was also reported. treatment with corticosteroid and supportive cares were started; however, her condition worsened. eventually, she was co...

hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.

gastrointestinal (gi) and hepatic manifestations are not uncommon in patients with systemic lupus erythematosus (sle). they include nonspecific symptoms as well as serious, life-threatening complications necessitating urgent, aggressive therapy. in addition to direct involvement of the gi system by the disease, many drug-induced side effects and opportunistic infections have gi and hepatic mani...

Toxic epidermal necrolysis-like lesions have been described in the setting of lupus erythematosus, and have been considered as a specific hyperacute variant of cutaneous lupus erythematosus, with features different from classical drug-related toxic epidermal necrolysis. We report here a series of three patients with lupus erythematosus who presented with severe worsening of their cutaneous dise...

The diagnostic significance of anti-double-stranded deoxyribonucleic acid (anti-dsDNA) determination was evaluated in a prospective manner from 1974 to 1982 in a group of 441 patients without systemic lupus erythematosus whose sera were found to contain antibodies to dsDNA on routine screening (Farr assay). Within one year 69% (304) of these patients fulfilled the preliminary American Rheumatis...

The objective of this article is to identify common and atypical features of systemic lupus erythematosus diagnosed following hepatitis B vaccination. We analyzed retrospectively the medical records of 10 systemic lupus erythematosus patients from different centers, who developed the disease following hepatitis B vaccination and determined the prevalence of different manifestations and the time...

Systemic lupus erythematosus (SLE) is an episodic, potentially fatal, multisystem autoimmune disease characterized by the presence of antinuclear antibodies especially to double stranded DNA. Bullous systemic lupus erythematosus is an extremely rare subset of lupus erythematosus. We report a 10-year-old boy with bullous SLE and nephrotic syndrome.

INTRODUCTION Systemic lupus erythematosus is a multi-system connective tissue disorder. Peripheral neuropathy is a known and underestimated complication in systemic lupus erythematosus. Ganglionopathy manifests when neuronal cell bodies in the dorsal root ganglion are involved. Autoimmune disorders are a known etiology, with systemic lupus erythematosus being a rare cause. CASE PRESENTATION A...