introduction: polycystic ovary syndrome (pcos) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction. presently, little is known about the primary factors that initiate pcos. chamomile flowers are used in alternative medicine for its anti-spasmolytic and anti-inflammatory effects. antispasmodic properties of chamomile ease menstrual cramps and lessen the possibilit...

Two hydrosoluble conjugates of 17β-estradiol (ED) and estradiol-17β-valerate (EV) with polyaspartamide polymer were prepared and characterized. ED and EV were first chemically modified and bound to poly[α,β-(N-2-hydroxyethyl-DL-aspartamide)]-poly[α,β-(N-2-aminoethyl-DL-aspartamide)] (PAHA), a hydrosoluble polyaspartamide-type copolymer bearing both hydroxyl and amino groups. ED was first conver...

Objective : Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, the effect of PCOS induction was studied using estradiol valerate. MaterialsAndMethods Adult ...

This paper describes zeroand first-order derivative spectrophotometric methods for determination of estradiol valerate in pharmaceutical preparations. The solutions of the standard and pharmaceutical samples were prepared in methanol. Absorbances of estradiol valerate were measured at 280 nm for zero-order by measuring height of peak from zero, at 292 nm for first-order derivative spectrophotom...

Introduction. Nephrotoxicity is one the side effect of cisplatin therapy and erythropoietin has been candidate as a nephroprotectant agent. However, its nephroprotective effect when it is accompained with estrogen has not been studied in female. Methods. 27 ovariectomized female Wistar rats divided into five groups. Groups 1 & 2 received estradiol valerate (0.5 mg/kg/week) for four weeks, and s...

Background: In recent years, a combination of hormones and agents in assisted reproductive technology (ART) cycles as a means of stimulating the ovary and developing more follicles. With respect to the positive effects of Estradiol Valerate on reproductive tissues and the impact on native genes of the egg that transferred to the embryo after fertilization, it seems that this agent can also effe...

objective: : polycystic ovary syndrome (pcos) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. in this study, the effect of pcos induction was studied using estradiol valerate. materials and methods: ad...

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder. Various constituents including flavonoids with biological activities including free radical scavenging, anti-lipoperoxidation and anti-inflammatory have been isolated from hawthorn. Due to adverse effect of PCOS on ovarian vascular remodeling as well as PCOS-induced oxidative stress, we aimed to study the hawthorn’s berri...

Background: Therapies available for thin endometrium are limited and mostly performed experimentally which most of these treatments have a similar function increase blood flow to the endometrium, causing it thicken develop. The aim study was compare effect estradiol valerate in combination with sildenafil on endometrial thickness infertile women before intrauterine insemination. Methods: In thi...