There is an increasing need to build an understanding of group facilitation in Distributed Requirements Engineering. Group facilitation is an important element of group approaches to Requirements Engineering, which is being challenged by the emergence of distributed practices in software specification and development. Thus thorough empirical investigation of human facilitation in computer-media...

Antidromic volleys in muscle nerves may facilitate monosynaptic reflexes originating from neighboring motoneurons. This facilitation has been studied in spinal cats. It is at its peak with a conditioning-test interval of 20 to 30 msec., and can last 50 to 100 msec. The threshold of facilitation is about the same as that of recurrent inhibition. Both phenomena appear to be activated by stimulati...

We have studied facilitation of the L-type calcium current in neurons acutely isolated from the ventrobasal nucleus of the rat thalamus. Currents were recorded after pretreatment with 1 microM omega-conotoxin GVIA and 5 microM omega-conotoxin MVIIC, to better isolate L-current. Long, strong depolarizations induced slow tail currents at negative voltages, but did not affect currents at voltages ...

We have characterized paired-pulse facilitation at Aplysia sensory neuron-to-motoneuron synapses. This simple form of very short-term synaptic plasticity displayed an unusual feature: it decreased dramatically with repeated testing. Synaptic depression at these synapses and this use-dependent decrease in paired-pulse facilitation occurred independently of each other. Paired-pulse facilitation w...

Facilitation of quanta1 release has been thought to be maximal immediately after the first action potential in the presynaptic terminal. However, at the frog neuromuscular junction at 0°C no facilitation was observed in response to direct nerve depolarization when the interval between stimulus pairs was less than 10 msec (Dudel, 1988), while at intervals of 20 msec and beyond, facilitation was ...

1. We studied two-pulse facilitation and delayed release at 0 degree C, because at low temperature facilitation is enhanced and extended whereas delayed release is increased. Our major goal was to test, by a number of approaches, the residual Ca2+ hypothesis of facilitation and delayed release. 2. As we increased the interval between pulses from 30 to 100-200 ms facilitation declined steeply. A...

an earlier overview of systematic reviews and a subsequent editorial on single-component versus multifaceted interventions to promote knowledge translation (kt) highlight complex issues in implementation science. in this supplemented commentary, further aspects are in focus; we propose examples from (kt) studies probing the issue of single interventions. a main point is that defining what is a ...