Ultrasound is very sensitive in diagnosing obstruction by demonstrating hydronephrosis (1, 2). Ultrasonography has great advantage over IVU in patients who have azotemia, contrast materialinduced allergy, are pregnant, fetal, or pediatric patients with no exposure to radiation. And ultrasonography can nicely visualize the both the renal parenchyma and the collecting system as well as causative ...

Antenatal hydronephrosis and vesicoureteral reflux (VUR) are common renal tract birth defects. We recently showed that disruption of the Robo2 gene is associated with VUR in humans and antenatal hydronephrosis in knockout mice. However, the natural history, causal relationship and developmental origins of these clinical conditions remain largely unclear. Although the hydronephrosis phenotype in...

  Abstract   Background: Hydronephrosis is the most common congenital condition that is detected   by prenatal ultrasonography. Moreover, the widespread use of prenatal ultrasonography   results in an increased recognition of fetal hydronephrosis. Prenatal hydronephrosis   is diagnosed at an incidence of 1:100 to 1:500 by ultrasonographic studies. The presence of hydronephrosis is not synonymou...

PURPOSE OF REVIEW Fetal hydronephrosis is the most common anomaly detected on antenatal ultrasound examination, and its significance and management remain controversial. This review aims to address the early postnatal evaluation of the child with prenatally diagnosed hydronephrosis. RECENT FINDINGS The risk of significant urological pathology increases with the severity of prenatal hydronephr...

Widespread use of ultrasonography has resulted in an increase in the recognition of fetal hydronephrosis. The enthusiasm that accompanied early interventions has been tempered by the experience and results obtained over the past 2 decades. The goal has remained the same: to identify patients with serious prenatal obstruction and to identify those which may benefit from intervention. Myelomening...

Purpose. It was to quantify the intraobserver and interobserver variability of the sonographic measurements of renal pelvis and classify hydronephrosis severity. Methods. Two ultrasonographers evaluated 17 fetuses from 23 to 39 weeks of gestation. Renal pelvis APD were taken in 50 renal units. For intraobserver error, one of them performed three sequential measurements. The mean and standard de...

BACKGROUND The information about fetal malformation findings during the ultrasound examination often comes unexpectedly, and the women and their partners may not necessarily receive any conclusive statement on the prognosis. A finding such as fetal hydronephrosis range from being a soft markers or mild anomaly, to a serious condition associated with neonatal morbidity and mortality. The aim of ...

Congenital obstructive nephropathy is the primary cause of chronic renal failure in children. Disorders of mitochondrial energy metabolism may be a primary factor underlying tubular cell apoptosis in hydronephrosis. The β-F1-ATPase (ATP5B) and electron transfer flavoprotein β subunit (ETFB) metabolic markers are involved in mitochondrial energy metabolism in other diseases. The aim of the prese...