introduction: cardiovascular abnormalities have been reported in liver cirrhosis (lc). in these patients, cardiac symptoms and physical signs occur as the liver functions worsen. cirrhosis is associated with hyper dynamic circulation and beta-adrenergic system changes responsible for the cardiovascular abnormalities. the purpose of the present study was to explore the echocardiographic findings...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : supervised exercise-based cardiac rehabilitation programs (crp) have been suggested to all patients, especially after myocardial infarction. however, the effects of cardiac rehabilitation on systolic function are controversial. the aim of this study was to examine the effects of an 8-week cardiac rehabilitatio...

The availability of choline during critical periods of fetal development alters hippocampal development and affects memory function throughout life. Choline deficiency during fetal development reduces proliferation and migration of neuronal precursor cells in the mouse fetal hippocampus and these changes are associated with modifications in the protein levels of some cell cycle regulators and e...

Glycogen storage disease type IV (GSD-IV) is an autosomal recessive disease caused by a deficiency in glycogen-branching enzyme (GBE1) activity that results in the accumulation of amylopectin-like polysaccharide, which presumably leads to osmotic swelling and cell death. This disease is extremely heterogeneous in terms of tissue involvement, age of onset and clinical manifestation. The most sev...

BACKGROUND Fetal tachycardia often leads to cardiac failure, which in experimental settings can be prevented by direct fetal glucose-insulin administration. In this study, we hypothesize that similar effects can be obtained indirectly by inducing maternal hyperglycemia. METHODS AND RESULTS Systolic and diastolic indices (dP/dt(max) and tau) of left ventricular function were measured by use of...

OBJECTIVE This article aims to present updated therapeutic options for fetal congenital heart diseases. METHODS Data source for the present study was based on comprehensive literature retrieval on fetal cardiac interventions in terms of indications, technical approaches and clinical outcomes. RESULTS About 5% of fetal congenital heart diseases are critical and timely intrauterine interventi...

Abstract Background Myocardial iron overload is the leading cause of death in patients with beta-thalassemia major. Combined therapy with deferiprone(DFP) and desferrioxamine (DFO)were suggested to be more effective than deferasirox(DFX) for removing heart iron. Deferasirox has recently been made available, but its long-term efficacy on cardiac function has not yet been established. Our study...

BACKGROUND Estimation of ventricular volume and mass is important for baseline and serial evaluation of fetuses with normal or abnormal hearts. Direct measurement of chamber wall volumes and mass can be made without geometric assumptions by 3D fetal echocardiography. Our goals were to determine the feasibility of using fast nongated 3D echocardiography for fetal volumetric and mass assessments,...

BACKGROUND Recently cardiomyocyte progenitor cells (CMPCs) were successfully isolated from fetal and adult human hearts. Direct intramyocardial injection of human CMPCs (hCMPCs) in experimental mouse models of acute myocardial infarction significantly improved cardiac function compared to controls. AIM Here, our aim was to investigate whether xenotransplantation via intracoronary infusion of ...