نتایج جستجو برای: fibroblast like synoviocytes

تعداد نتایج: 684939  

Journal: :Clinical and experimental rheumatology 2007
M M C Steenvoorden R A Bank H K Ronday R E M Toes T W J Huizinga J DeGroot

OBJECTIVE In vitro models for joint diseases often focus on a single cell type, such as chondrocytes in osteoarthritis (OA) or fibroblast-like synoviocytes (synoviocytes) in rheumatoid arthritis (RA). However, these joint diseases affect the whole joint and interaction between chondrocytes and synoviocytes may play an important role in disease pathology. The current study was designed to study ...

Journal: :Archives of histology and cytology 2002
Junko Nio Ayaka Yokoyama Masahiro Okumura Toshihiko Iwanaga

The synovial intima is composed of two types of synoviocytes: absorptive macrophages and secretory, fibroblast-like F cells. Many studies have tried to observe synoviocytes by scanning electron microscopy (SEM) but failed to reveal the entire shape of synoviocytes because they are deeply embedded in the interstitial matrix. The present study, primarily employing SEM observation of NaOH macerate...

2015
Stine Mandrup Andreassen Lise C. Berg Søren Saxmose Nielsen Annemarie T. Kristensen Stine Jacobsen

BACKGROUND Studies in humans have shown that haemostatic and inflammatory pathways both play important roles in the pathogenesis of joint disease. The aim of this study was to assess mRNA expression of haemostatic and inflammatory factors in cultured equine fibroblast-like synoviocytes exposed to lipopolysaccharide (LPS), fibrinogen and thrombin. Synovial membranes were collected from metacarpo...

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