statement of problem: adhesion to root canal dentin is one of the necessary characteristics of endodontic sealers. mta fillapex (angelus, londria, pr, brazil) is one of the recently introduced mta-based sealer. only a limited number of studies have evaluated the bonding of this sealer to the dentin, with conflicting results. objectives: the purpose of this study was to evaluate the bond strengt...

The aim of the present study was to evaluate the effect of calcium hydroxide dressing on the bond strength of three commercially available endodontic sealers (MTA Fillapex, Sealapex, and AH Plus) to root canal dentin. Sixty slices of extracted human canines were obtained from cervical, middle, and apical root thirds. Root canals were standardized and specimens were filled and divided into six g...

Aim This laboratory study evaluated the pH and antibacterial activity of Endo CPM Sealer and MTA Fillapex by two different methods, using White MTA and Endofill as references for comparison. Methodology Antibacterial activity was evaluated against Enterococcus faecalis (ATCC 29212). The agar diffusion test (ADT) was performed to evaluate the effect before setting. The materials were placed in f...

Introduction: Mineral trioxide aggregate (MTA) as an alternative material to gutta-percha for obturation of root canal in special cases has several drawbacks. The purpose of this study was to compare the apical sealing ability of a new MTA-based sealer versus MTA. Materials and Methods: A total of 36 canals of extracted maxillary central incisors were instrumented and randomly divided into 3...

introduction: this study aimed to compare the cytotoxicity of mta fillapex, ah-26 and apatite root canal sealers at different times after mixing. methods and materials: in this in vitro study, mta fillapex, ah-26 and apatite root canal sealer were spilled uniformly by 40 µm mesh in a 96-well plate. then, human fetal foreskin fibroblast cell line (hfff2) were added to each sealer cell culture me...

Objective: The aim of the present study was to evaluate the antimicrobial activity of new bioceramic root canal sealers Smartpaste Bio, MTA Fillapex and AH plus. Materials and Methods: The antimicrobial activity of sealers was tested by agar diffusion method on the surface of agar plates of Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and Escherichia co...

The aim of this study was to evaluate the influence of diabetes mellituson tissue response and mineralization ability of Sealapex®and MTA Fillapex® sealers. Twenty-four Wistar rats were divided into two groups: diabetic and non-diabetic. The materials were placed in polyethylene tubes and implanted into dorsal connective tissue of rats for 7 and 30 days. Six animals from each group received inj...

The aim of this study was to compare the in vitro cytotoxicity of white mineral trioxide aggregate (MTA), MTA Fillapex® and Portland cement (PC) on human cultured periodontal ligament fibroblasts. Periodontal ligament fibroblast culture was established and the cells were used for cytotoxic tests after the fourth passage. Cell density was set at 1.25 X10 4 cells/well in 96-well plates. Endodonti...

The aim of the present study was to evaluate the cytotoxicity of root canal sealers under conditions closely resembling a clinical reality. A primary human fibroblast cell line was seeded in 24-well acrylic plates with Dulbecco's modified Eagle's medium supplemented with 10% serum fetal bovine (SFB) and incubated for 24 h. Root canals from premolars were filled and individually attached to nylo...

Human dental pulp stem cells (HDPSCs) are of special relevance in future regenerative dental therapies. Characterizing cytotoxicity and genotoxicity produced by endodontic materials is required to evaluate the potential for regeneration of injured tissues in future strategies combining regenerative and root canal therapies. This study explores the cytotoxicity and genotoxicity mediated by oxida...