Salmonella enterica serotype typhimurium (S. typhimurium) DT104 (DT104) first emerged as a major pathogen in Europe and is characterized by its pentadrug-resistant pattern. It has also been associated with outbreaks in the United States. The organism typically carries resistance to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline. The mechanism of chloramphenicol resist...

OBJECTIVES A florfenicol-resistant Pasteurella trehalosi isolate from a calf was investigated for the presence and the location of the gene floR. METHODS The P. trehalosi isolate 13698 was investigated for its in vitro susceptibility to antimicrobial agents and its plasmid content. A 14.9 kb plasmid, designated pCCK13698, was identified by transformation into Pasteurella multocida to mediate ...

The purpose of this study was to compare the efficacy and cost-effectiveness of florfenicol versus tulathromycin for initial treatment of undifferentiated fever in fall-placed steer calves that received metaphylactic tilmicosin on arrival at the feedlot. No significant differences (P > .10) were observed in undifferentiated fever relapses or the crude case fatality rate. Calves treated with flo...

Pathogens are an important and significant hazard for human and animal health. In recent years, antibiotics are used to treat different types of infection caused by bacterial agents. In veterinary medicine, antibiotics injected into hatching eggs to eliminate pathogens and prevention of egg transmission of disease, but the adverse effects of drugs have always been a major conc...

Sir, The Gram-negative bacterium Haemophilus parasuis is the causative agent of Glässer’s disease, which is characterized by various combinations of meningoencephalitis, polyserositis, polyarthritis and bacterial pneumonia, resulting in major economic losses to the swine industry worldwide. Florfenicol is used exclusively in veterinary medicine and was approved for the treatment of porcine resp...

The purpose of this study was to compare the efficacy of a new combination drug, florfenicol-flunixin meglumine, with tulathromycin for initial treatment of undifferentiated fever (UF) in fall-placed calves that received metaphylactic tilmicosin on arrival at the feedlot. No significant differences were observed in UF relapses between the two drugs. Calves treated with florfenicol-flunixin had ...

Trong nghiên cứu này chúng tôi đã phát triển một phương pháp định lượng nhanh và chính xác Chloramphenicol Florfenicol tồn dư trong thịt gia cầm bằng máy sắc ký khối phổ siêu hiệu năng UPLC-MS/MS. Điều kiện của gồm cột ký: C18; 50×2,1mm; 1,7µm, pha động: ACN: 0,1% acid formic/H20 (90:10), tốc độ dòng: 0,3 mL/phút, thể tích tiêm: 2µL. Phương trình bày kết quả khả quan về nhạy, thu hồi cầm. được ...

The antibiotic residues in milk are a well-known serious problem and pose several health hazards to consumers. We have described a simple, rapid, and inexpensive DLLME-HPLC/UV technique for the extraction of chloramphenicol and florfenicol residues in milk samples. Under the optimum conditions, linearity of the method was observed over the range 0.02-0.85 µg/L with correlation coefficients > 0....

Background: Florfenicol (Ff) is a synthetic antibiotic with a broad antibacterial spectrum and high therapeutic effectiveness that was specifically developed for veterinary use as well as, doxcycline is an antibiotic synthetically derived from oxytetracycline. Methods: In the present study, the in-vitro efficacy of Ff and doxcycline against Salmonella entertidis and Escherichia coli (Serotype O...

AIM The aim of this study was to evaluate the impact of therapeutic and high doses of florfenicol on kidney and liver functional indicators in goat species. MATERIALS AND METHODS Six mature, healthy goats (combine breed and sex) with average weight 25 kg were selected for this study. The therapeutic (20 mg/kg b.w.) and high doses (40 and 60 mg) of florfenicol were administered for 3 days with...