BACKGROUND The deposition and oligomerization of amyloid β (Aβ) peptide plays a key role in the pathogenesis of Alzheimer's disease (AD). Aβ peptide arises from cleavage of the membrane-associated domain of the amyloid precursor protein (APP) by β and γ secretases. Several lines of evidence point to the soluble Aβ oligomer (AβO) as the primary neurotoxic species in the etiology of AD. Recently,...

A novel 3D donor material (SF8TBT) based on spiro-fluorene has been developed. Compared with the corresponding 1D linear molecule, the OPVs of this 3D donor exhibited power conversion efficiencies of 4.82%, much higher than that of 1D small molecules (1.69%).

A fluorene derivative having both bromo and formyl groups exhibited bright phosphorescence emission in common organic solvents at room temperature. The absolute phosphorescence quantum yield reached 5.9% in chloroform at 298 K. When the fluorene derivative was incorporated into a poly(methyl methacrylate) film, the phosphorescence emission was similarly observed even under air at room temperatu...

This study was conducted to investigate the occurrence of PAH degrading microorganisms in two river systems in the Western Cape, South Africa and their ability to degrade two PAH compounds: acenaphthene and fluorene. A total of 19 bacterial isolates were obtained from the Diep and Plankenburg rivers among which four were identified as acenaphthene and fluorene degrading isolates. In simulated b...

We report a new synthetic route to 5,11-disubstituted indeno[1,2-b]fluorene-6,12-diones that is amenable to larger scale reactions, allowing for the preparation of gram amounts of material. With this new methodology, we explored the effects on crystal packing morphology for the indeno[1,2-b]fluorene-6,12-diones by varying the substituents on the silylethynyl groups.

Data are reported on the triplet states of a series of fluorene-based A-alt-B type alternating copolymers based on pulse radiolysis-energy transfer and flash photolysis experiments. From the pulse radiolysis experiments, spectra are given for eight copolymers involving phenylene, thiophene, benzothiadiazole, and oligothienylenevinylene groups. Quantum yields for triplet-state formation (PhiT) h...

Polyimide (PI) optical films with high glass transition temperatures (high-Tg), transparency, and low retardations (low-Rth) are highly desired in advanced optoelectronic applications. However, the standard PI usually suffer from deep colors, anisotropies limited Tg values. In current work, a series of semi-alicyclic colorless transparent (CPI) were developed hydrogenated pyromellitic dianhydri...

Triplet energy transfer (TT), a key process in molecular and organic electronics, generally occurs by either strongly distance-dependent single-step tunneling or weakly distance-dependent multistep hopping. We have synthesized a series of pi-stacked molecules consisting of a benzophenone donor, one to three fluorene bridges, and a naphthalene acceptor, and studied the rate of TT from benzopheno...

This paper deals with a very common problem on spectrofluorimetry: the inner-filter effect. This limitation has made spectrofluorimetry into a disadvantageous technique for the quantification of individual compounds in complex mixtures, however, a lot of papers have quantified compounds as fluorene in mixtures where other Polycyclic Aromatic Hydrocarbons (PAHs) absorb part of the energy emitted...

Polycyclic aromatic hydrocarbons (PAH) are toxic, mutagenic, and carcinogenic compounds. Removal of these compounds has a great importance for environment. Removal of PAHs from soil is difficult as these chemicals are persistent in the soil. In this research, bioremediation of soil contaminated by (PAH) using Bacillus subtilis DSMZ 3256 (B.subtilis) strains was studied. The effect of electrokin...