determination of terazosin hydrochloride dihydrate (trz) in drug substance and tablets was studied by fluorimetric techniques. the fluorimetric methods are based on: (1) measurement of the native fluorescence of the drug in water at 750 nm after excitation at 330 nm. (2) sensitizing the native fluorescence by formation a binary complex of drug with aqueous uranyl acetate (0.1% w/v) at the same ...

Light up, light up: The fluorimetric detection of different biomacromolecules is accomplished with 3-(4-N,N-dimethylaminophenylnaphtho[1,2-b]quinolizinium as a fluorescent probe. This molecule shows light-up effect in the presence DNA, RNA and bovine serum albumin (BSA) emission energies, intensities, lifetimes. These effects may be used for differentiation between cell compartments.

A simple, rapid and automatic fluorimetric method for the determination of total ascorbic acid is described. The method makes use of the stopped-flow mixing technique in order to achieve the rapid oxidation of ascorbic acid by dissolved oxygen to dehydroascorbic acid, which then reacts with o-phenylenediamine to form a fluorescent quinoxaline. The initial rate and fluorescence signal of this sy...

BACKGROUND Circulating autoantibodies to pancreatic glutamic acid decarboxylase (GAD65; the 65-kDa isoform of glutamic acid decarboxylase), protein tyrosine phosphatase-like protein IA-2, and insulin can be used as predictive markers of type 1 diabetes. We developed a novel assay for the detection of IA-2 autoantibodies (IA-2As) in serum based on time-resolved fluorimetry, hypothesizing that th...

Differences in fluorescence intensity between FMN and FAD at high and low pH values were utilized to determine the concentration of each nucleotide. Amounts down to 1 pmol were measurable. The FMN and FAD contents of pancreatic islets of obese-hyperglycaemic mice (gene symbol ob/ob) were compared with those of the exocrine pancreas, the liver and heart muscle. As expected, the FAD content of ea...

We developed a noninvasive rapid fluorimetric method for the investigation of growth of adhering (benthic) phototrophic microorganisms. The technique is based on the sensitive detection of the in vivo fluorescence of chlorophylls chlorophyll a and bacteriochlorophyll a and monitors increases in signal over time as an indicator for growth. The growth fluorimeter uses modulated excitation light o...

Обсуждается применение флуориметрического метода анализа в экологическом мониторинге рек г. Твери и Иваньковского водохранилища. Приведены результаты содержания нефтепродуктов ряде водных объектов Тверской области. The application of the fluorimetric method analysis in ecological monitoring rivers city Tver and Ivankovo reservoir is discussed. results content oil products a number water bodies ...