The weight difference between large, small and unselected strains of mice were maintained when blastocysts of each genotype were transferred to unselected control recipients, suggesting that foetal genotype was an important factor in determining prenatal body size. The asynchronous transfer of large, small and unselected embryos resulted in a highly significant (P less than 0-001) elevation of ...

Thyroid cancer is the most common endocrine malignancy, more frequently diagnosed in young women during childbearing age and approximately 10% of all thyroid cancers are diagnosed during pregnancy or in the early post-partum period. Thyroid cancer in young people has generally an excellent prognosis, and survival among women with thyroid cancer diagnosed during pregnancy may not differ from tha...

Several clinical and experimental studies support the hypothesis that foetal programming is an important determinant of nephropathy, hypertension, coronary heart disease, and type 2 diabetes during adulthood. In this paper, the renal repercussions of foetal programming are emphasised, and the physiopathological mechanisms are discussed. The programming of renal diseases is detailed based on the...

BACKGROUND/OBJECTIVE An adequate supply of long-chain polyunsaturated fatty acids (LC PUFA) promotes foetal health and development, whereas generally, trans fatty acids (tFA) are considered to negatively interfere with LC PUFA metabolism. Nevertheless, to date, limited data concerning separate trans C18:1, such as t9 and t11, are available for maternal and foetal blood. Therefore, in this study...

1. The liver of the domestric fowl (Gallus gallus) remains capable of conjugating o-aminophenol with glucuronic acid after 8 days' culture. The pathway of o-aminophenyl glucuronide formation in cultured liver, as in fresh tissue, includes the enzyme UDP-glucuronyltransferase. 2. UDP-glucuronyltransferase activity in chick-embryo liver increases on culture from very low to adult values within 6-...

enlargement andreduced corticalvolume arecorrelatesofchronic schizophrenia.We investigatedwhether genetic risk for psychosis is related to differences in foetal brain development asmeasuredby prenatalultrasonography.Routine foetal cerebralmeasures at19^23 weeks of gestationwere comparedbetweenthe offspring of 35 womenwith a historyof psychosis and105 controlwomenmatched for gestational age.Over...

BACKGROUND Perinatal, foetal and neonatal mortality statistics are important to show the development of a health care system in a country. However, in our country there are very few national and regional data about the changing pattern of perinatal neonatal mortality along with the development of new technologies in this area. AIMS Evaluation of the changes in mortality rates and the causes o...

We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function. Animals were killed prepubertally at d25 and as adults at d90. Plasma samples were taken for hormone analysis and ovaries serial sectioned for morpho...

The goal of the study was to analyse statistically the survey of measurable parameters distinguishing human facial skeleton as well to construct mathematical model describing foetal facial skeleton selected features. The material consisted of 112 foetuses (44 females – 39.29% and 76 males – 60.71%) in the CRL: 83-245 mm, aged 4-7 months of foetal life. The whole of the examined material origina...

Knowledge of the course of the pancreaticoduodenal arteries is of great importance in pancreatic surgery. Lack of care in the preparation of these vessels may lead to ischaemia or necrosis of the duodenum, the first loop of the jejunum, the head of the pancreas and even the liver, bile ducts and transverse colon. In such events, the surgeon would need to diagnose the course of the vessels and t...