BACKGROUND Thymosin beta 4 (Tbeta(4)) is a member of beta-thymosins, a family of peptides that play essential roles in many cellular functions. A recent study from our group suggested a role for Tbeta(4) in the development of human salivary glands. The aim of this study was to analyze the expression of Tbeta(4) in the human gut during development, and in the adult. METHODOLOGY/PRINCIPAL FINDI...

Abstract Background Intrauterine growth restriction (IUGR) is a common diagnosis in obstetrics and carries an increased risk of perinatal mortality morbidity. Identification IUGR crucial because proper evaluation management can result favourable outcome. Cardiovascular dysfunction remodelling central feature IUGR. The aim the study was to use left modified myocardial performance index (MPI), as...

This study was conducted to evaluate foetal/pregnancy losses following slaughtering of food animals at Nsukka Municipal Abattoir Enugu State, Nigeria over a period three months (April June). The pregnancy status each animal determined tentatively by visual observation and palpation the exposed uterus after slaughtering. Attempts were made recover embryos from dams with structures suggestive flu...

Background: To study the histogenesis of prostate gland in human foetuses. ‘Prostates’ is a Greek word which literally means “one who stands before”, protector, guardian. It important from clinical point view as it undergoes benign enlargement fifth decade, hence attracting attention males around this age and simultaneously clinicians. Materials Methods: 100 foetuses different gestational ages ...

the deleterious effects of morphine sulphate addiction on the central nervous system are welldocumented. previous studies have shown that the passage of morphine from the placenta barrier caninfluence the normal development of embryos, such as those of humans, by specific mechanisms. so, forthe first time, for the purpose of investigating the effects of morphine sulphate on pregnant animals,thr...

BACKGROUND Cancer-cachexia induces a variety of metabolic disorders of protein turnover and is more pronounced when associated with pregnancy. Tumour-bearing pregnant rats have impaired protein balance, which decreases protein synthesis and increases muscle breakdown. Because branched-chain amino acids, especially leucine, stimulate protein synthesis, we investigated the effect of a leucine-ric...

THE frequent discovery of tears of the dura mater septa associated with subdural cerebral haemorrhage, in foetuses dying during the course of labour, was one of the most striking features of this investigation. Out of 168 fresh foetuses the tentorium cerebelliwas found torn in8i (48 per cent.), associated with tearing of the falx cerebri in five cases and with subdural cerebral haemorrhage in a...

Primary cardiac tumours in the foetuses and neonates are uncommon. Foetuses with cardiac tumour have risk for heart failure and hydrops fetalis. Therefore, an early decision for delivery should be made in the evidence of foetal compromise. Early neonatal care varies on tumour size, type, location and obstructive features. Antenatal detection of foetal cardiac tumours ensures better prenatal and...