Anti-müllerian hormone (AmH) or müllerian inhibiting substance (mIS), is a dimeric protein part of the transforming growth factor (TGF)-beta subfamily. It plays two important roles in follicle genesis. First, it delays entrance of primordial follicle into pool of follicles in growth and secondly, it decreases the sensitivity of ovarian follicle toward follicle-stimulating hormone (FSH). The ova...

The CAMP-dependent protein kinase (EC 2.7.1.37; ATP:protein phosphotransferase) inhibitor in Sertoli cell-enriched rat testis has been shown to be specifically stimulated by follicle-stimulating hormone in uiuo. Intraperitoneal injection of follicle-stimulating hormone (100 pg of NIH-FSH-S12) induced a significant increase in protein kinase inhibitor 8 h after injection. Maximal stimulation of ...

A highly purified follicle-stimulating hormone from human pituitary glands has been prepared by ammonium sulfate and ethanol fractionation, gel filtration on Sephadex G-100, ion exchange chromatography on carboxymethyl cellulose, zone electrophoresis on cellulose columns, and preparative continuous flow polyacrylamide gel electrophoresis. The final product has shown lO,OOO-fold purification ove...

A highly purified follicle-stimulating hormone from human pituitary glands has been prepared by ammonium sulfate and ethanol fractionation, gel filtration on Sephadex G-100, ion exchange chromatography on carboxymethyl cellulose, zone electrophoresis on cellulose columns, and preparative continuous flow polyacrylamide gel electrophoresis. The final product has shown lO,OOO-fold purification ove...

background: azadirachta indica is a tree with most of the parts having various medicinal values. it is however popular because of its high potencies, as antimalarial and anti-fertility agents, which the locals still exploit. objective: we investigated the effect of the methanol leaf extract on the serum levels of the pituitary-gonad hormones and the histo-morphology of the ovary and uterus of a...

OBJECTIVE Aneurysmal subarachnoid hemorrhage puts patients at high risk for the development of pituitary insufficiency. We evaluated the incidence of pituitary dysfunction in these patients and its correlation with clinical outcome. METHODS Pituitary function was tested in 66 consecutive patients in the first 15 days after aneurysmal subarachnoid hemorrhage. The following were measured in all...

Aim. This study aimed to describe a distinct subpopulation of azoospermic patients with isolated elevation follicle-stimulating hormone (iFSH) and poor outcomes microdissection testicular sperm extraction (microTESE). Materials methods. A retrospective analysis microTESE was conducted among 565 non-obstructive azoospermia (NOA). Testicular pathology assessed by the dominant histological pattern...