thyroid cancer, the most common endocrine malignancy worldwide, originates from follicular epithelial cells. it is classified as a well-differentiated thyroid carcinoma (wdtc), which includes both follicular (ftc) and papillary types (ptc), poorly differentiated thyroid carcinomas (pdtc), anaplastic thyroid carcinoma (atc), and/or arising from para-follicular calcitonin producing cells involve m...

In this article, we present a case of diffuse follicular variant papillary thyroid carcinoma with pituitary metastasis, which is rare cause metastasis. The an uncommon carcinoma. A 74-year-old male was presented weakness, fatigue, and decreased appetite. patient diagnosed secondary adrenal insufficiencies. Imaging revealed mass suprasellar extension, right cavernous sinus invasion, optic chiasm...

AIMS AND BACKGROUND Lymph node metastases are rare in patients with follicular thyroid carcinoma, with an average incidence of 5.5% of all cases reported in the literature. In the present study we focused on the search for risk factors predictive of lymph node involvement in patients with follicular thyroid carcinoma to plan the most appropriate management and follow-up. METHODS AND STUDY DES...

Thyroid carcinomas are the most frequently occurring tumours in the endocrine system. Metallothioneins (MT) and Ki-67 proteins are present in intensely proliferating cells, and their expression has been observed in numerous tumours, including thyroid tumours. The purpose of this study was to analyse the relationship between intensity of MT expression and Ki-67 antigen on one hand and histologic...

Mutation of the BRAF gene is common in thyroid cancer. Follicular variant of papillary thyroid carcinoma is a variant of papillary thyroid carcinoma that has created continuous diagnostic controversies among pathologists. The aims of this study are to (1) investigate whether follicular variant of papillary thyroid carcinoma has a different pattern of BRAF mutation than conventional papillary th...

We report a rare case of mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid. A 27-year-old Chinese female complained of a single thyroid nodule for 2-3 months. Needle aspiration revealed suspicious papillary carcinoma and thyroidectomy performed later showed mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid which was extremely rare. W...

Thyroid-like follicular carcinoma of the kidney is an extremely rare histological variant of renal cell carcinoma. It was described only recently and is not included in the World Health Organization classification of renal tumors. This tumor characteristically shows similar histology to thyroid follicular carcinoma but lacks typical thyroid markers. Herein, we report a new case of thyroid-like ...

Fine needle aspiration biopsy (FNAB) of the thyroid is limited in distinguishing hyperplastic nodular goiter from true follicular neoplasm and in separating follicular adenoma from follicular carcinoma. The present study was done to evaluate if the morphologic and morphometric investigations and silver staining of nucleolar organizer regions (NORs), either alone or in association would help to ...

OBJECTIVE Endothelin-1 (ET-1) may play a role in carcinogenesis. ET-1 axis is overexpressed in thyroid carcinoma. We investigated the expression and the production of ET-1 by thyroid cancer cells as well as the effect of ET-1 receptor antagonism on cell proliferation. DESIGN Human papillary and follicular thyroid carcinoma cell lines were cultured. MEASUREMENTS (i) Prepro-ET-1, ET-1 recepto...