TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by knoevenagel condensation, michael addition and cyclodehydration of dimedone. this reaction was carried out through condensation of dimedone and various aromatic aldehydes in the presence of task-specific brønsted acidic ionic liquid under solvent free conditions. the catalyst could be recycled five times without si...

this article reports on the findings of a study that investigated the impact of manipulating task performance conditions on listening task performance by learners of english as a foreign language (efl). the study was designed to explore the effects of changing complexity dimensions on listening task performance and to achieve two aims: to see how listening comprehension task performance was aff...

ISSN 2277 – 5048 | © 2012 Bonfring Abstract--The biological role of many RNA crucially depends on their structure. The in depth understanding of the secondary structure of RNA would provide a better insight in to their functionality. Predicting secondary structure of RNA is the most important factor in determining its 3D structure and functions. This work proposes a model for exploring the feat...

Due to instant availability and low cost, machine translation is becoming popular. Machine translation mediated communication plays a more and more important role in international collaboration. However, machine translators cannot guarantee high quality translation. In a multilingual communication task, many in-domain resources, for example domain dictionaries, are needed to promote translation...

In this paper, we first study the material stability of nanostructured materials via the continuum linearized stability analysis technique with the temperature-related Cauchy–Born (TCB) rule. As a temperature-related homogenization technique, the TCB rule considers the free energy instead of the potential so that temperature effects on material stability can be investigated. In addition, we dev...

Theoretical results on HTN planning are mostly related to the plan existence problem. In this paper, we study the structure of the generated plans in terms of the language they produce. We show that such languages are always context-sensitive. Furthermore we identify certain subclasses of HTN planning problems which generate either regular or context-free languages. Most importantly we have dis...