For many years, melatonin has been known to interact with circadian rhythms. New evidence indicates that melatonin acts as a free radical scavenger and antioxidant. Moreover, melatonin prevents apoptosis in different types of cells, because it induces mRNA levels of several antioxidant enzymes. It is evident that melatonin is involved in the cellular bioenergetic system as a mechanism that coun...

The Bogoliubov free energy functional is analysed. The functional serves as a model of a translation-invariant Bose gas at positive temperature. We prove the existence of minimizers in the case of repulsive interactions given by a sufficiently regular two-body potential. Furthermore, we prove existence of a phase transition in this model and provide its phase diagram.

A comparative DNA scission activity study of azaferrocene, N-methyl-azaferrocene iodide and 3,3',4,4'-tetramethyl-1,1'-diphosphaferrocene (featuring iron in a +2 oxidation state), along with ferrocene (iron +2) and ferrocenium (iron +3) cation is described. Experiments indicate a high cleavage activity of azaferrocene and its N-methyl derivative in DMSO. DNA cleavage activity can be slowed down...

To develop more potent small molecules with enhanced free radical scavenger properties, a series of N-substituted isatin derivatives was synthesized, and the cytoprotective effect on the apoptosis of PC12 cells induced by H2O2 was screened. All these compounds were found to be active, and N-ethyl isatin was found with the most potent activity of 69.7% protective effect on PC12 cells. Structure-...

Consider a charged Bose gas without self-interactions, confined in a three dimensional cubic box of side L ≥ 1 and subjected to a constant magnetic field B 6= 0. If the bulk density of particles ρ and the temperature T are fixed, then define the canonical magnetization as the partial derivative with respect to B of the reduced free energy. Our main result is that it admits thermodynamic limit f...

This study is about Complexes of Li doped silicon carbide nanotube with Thymine and Cytosine ingas phase and aqueous solutions. Li doped silicon carbide nanotube and its pyrimidine nucleobasecompounds were first modeled by Quantum mechanical calculations in gas phase and in water.Calculated binding energies indicated the stronger ability of thymine to functionalize silicon carbidenanotube than ...

The vacuum energy density or free energy of a free charged Bose gas at nonzero densities is studied in the context of the debate about Multiplicative Anomalies. Some ζ-function regularised calculations of the free energy in the literature are reexamined, clarified and extended. A range of apparently distinct answers can obtained. Equivalent dimensional regularisation results are also presented ...

Flavonoids and organic acids were recommended in the literature as the main active constituents of Camptosorus sibiricus Rupr. Assay-guided fractionation led to the isolation of 9 flavonoids and 8 phenolic acids. All compounds were tested for DPPH scavenging activity, SOD-like and aldose reductase inhibition. Among them, compounds 1, 2, 3, 5, 6, 7, 8, 9, 11, 15 showed activities. The most activ...

Since aging is the most important risk factor for variety of diseases, the discovery of a wide range of chemical modulators of aging in model organisms encourages new strategies for targeting age associated diseases. Simple genetic manipulation leads to long-lived and healthy animals, so any compound which could have similar effect would prove a boon to mankind. In the present study, effect of ...

A lower bound is derived on the free energy (per unit volume) of a homogeneous Bose gas at density ̺ and temperature T . In the dilute regime, i.e., when a̺ ≪ 1, where a denotes the scattering length of the pair-interaction potential, our bound differs to leading order from the expression for non-interacting particles by the term 4πa(2̺−[̺−̺c]+). Here, ̺c(T ) denotes the critical density for Bose-Ein...