INTRODUCTION There is a need for clinically administered instruments capable of detecting executive dysfunction in dementia. OBJECTIVE The translation and validation of Executive Battery 25 (EB25) and a short version for screening of executive dysfunction in dementia. METHODS The original battery was translated and validated using convergent and divergent correlation in 66 mild dementia pat...

Older adults' heightened susceptibility to false memories has been linked to compromised frontal lobe functioning as estimated by Glisky and colleagues' (Glisky, Polster, & Routhieaux, 1995) neuropsychological battery (e.g., Butler, McDaniel, Domburg, Price, & Roediger, 2004). This conclusion, however, rests on the untested assumption that young adults have uniformly high frontal functioning. W...

The aim of this study was to analyze the efficiency a physical activity program on executive performance in obese adolescents. Fifteen adolescents (5 males and 10 females), with mean age 14.73 years an IMC 36.74 participated study. None participants presented compulsive eating disorder when screened by Binge Eating Scale. A pretest posttest assessment, twelve months later, conducted using neuro...

Background: The prevalence of cognitive impairment among patients with epilepsy is about 70%. There is still no approved medication for the treatment of this problem. Objectives: The present study aims to assess the safety and efficacy of memantine in improving the cognitive function of patients with epilepsy. Materials & Methods: This is a pilot, randomized, double-blind, placebo-controlle...

Recent neuroimaging studies and neuropsychological test findings support the contention that prefrontal dysfunction is associated with psychopathic personality traits and antisocial behavior. However, conflicting results have arisen regarding performance on measures of frontal executive function. We administered a neuropsychological test battery consisting of measures sensitive to frontal lobe ...

Distinct cognitive deficits have been described in Bipolar disorder (BD), including executive impairments, commonly attributed to frontal dysfunction. However, recent attention has been paid to the heterogeneity of cognitive functioning in this population, suggesting that the executive deficits observed in BD might be due to a loss in fluid intelligence (g). Following our previous line of inves...

BACKGROUND The prevalence of negative symptoms in schizophrenic patients seems to be an important indicator for treatment response and prognosis. Although negative symptoms have often been attributed to frontal lobe anomalies, neuropsychological and anatomical findings do not explicitly support this assumption. Since knowledge about the cerebral correlate of negative symptoms in schizophrenia m...