Digital breast tomosynthesis (DBT) is being developed as an approach to generate images that may improve the sensitivity and specificity of mammography. Current radiographic approaches to mammography produce two-dimensional (2D) images. These 2D systems can have limitations due to overlapping tissue in the breast that may hide lesions (cancers) or cause benign masses to appear suspicious. DBT, ...

Effects of x-ray scattering on full-field digital mammography are analyzed with the scattering model of Seibert and Boone [Med. Phys. 15, 567-575 (1988)]. A new method is introduced for the estimation of model parameters from measurements. It is shown that with breasts thinner than a certain threshold, removing the anti-scatter grid leads to an improved contrast-to-noise ratio with a smaller pa...

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To explore the impact of radiolucent breast cushions on breast pain and image quality of full field digital mammography (FFDM) in screening subjects. The American College of Radiology (ACR) phantom and fifty-four women were enrolled in this study. Use of cushions reduced pain (p < 0.001). The imaging quality with cushions was inferior to those without cushions in phantom studies (p ≦ 0.01), on ...

Title of dissertation: TASK SPECIFIC EVALUATION METHODOLOGY FOR CLINICAL FULL FIELD DIGITAL MAMMOGRAPHY Haimo Liu, Doctor of Philosophy, 2012 Dissertation directed by: Professor Iacovos Kyprianou Department of Bioengineering Purpose: The purpose of this dissertation is to evaluate the image quality of clinical Full Field Digital Mammography (FFDM) systems. This is done by evaluating image acqui...

Screen-film mammography has been studied extensively for the past 30 years, and because of many large randomized screening trials, it is known to reduce breast cancer mortality by approximately 18%-30% (1,2). The decline in the rate of breast cancer death in the past few years may be due in part to the widespread use of this imaging test (3,4). However, while standard screen-film mammography is...