A novel electrochemical assay to quantify transglutaminase activity is reported. The assay is based on the enzyme-controlled diffusion of Fe(CN)6(3-/4-) through amino-functionalized nanochannels of a mesoporous silica thin film on a Au surface in the presence of N-benzyloxycarbonyl-L-glutaminylglycine.

Mesoporous silica thin films and nanoparticles prepared by surfactant-templated sol–gel techniques are versatile substrates that can be easily erivatized with active molecules to create functional materials. By exploiting the chemical and physical differences that exist in different regions f the mesostructure, active molecules can be deliberately placed using one-pot techniques, or they can be...

Organo-modified mesoporous silica nanoparticles, loaded with ibuprofen into the pores and functionalized on the external surface with a stable Gd(iii)-DOTA-monoamide chelate, were prepared and explored as potential theranostic probes.

trans-1,2-Diaminocyclohexane functionalized mesoporous silica was applied as an ideal catalyst for asymmetric Michael addition of various nitroalkane derivatives. Short channels and plugs in the pore structure offered chiral enhancement in Michael addition.

The present work describes the fabrication of functionalized mesoporous silica based antireflective-cum-hydrophobic coatings on textured solar cover glasses via a spray-coating technique exhibiting enhanced photo-current density.

In this paper, we bring forward an effective strategy, solvothermal postsynthesis, to prepare ordered mesoporous silica materials with highly branched channels. Structural characterizations indicate that the titled mesoporous materials basically have the cubic double gyroidal (space group Ia-3d) structure with small fraction of distortions. The mesopore sizes and surface areas can be up to 8.8 ...

Mesoporous silica functionalized with a 2-hydroxy-naphthyl moiety has been synthesized and characterized by standard techniques like powder X-ray diffraction, N2 adsorption/desorption studies, transmission electron microscopy and spectral studies like FT-IR, UV-visible, fluorescence and 13C and 29Si solid state NMR. The functionalized silica material showed significant enhancement in its emissi...

We present a novel therapeutic nanoplatform based on mesoporous silica nanoparticles encapsulating ferulic acid/gemcitabine and functionalized with anti-GPC1 antibodies to target human pancreatic cancer (PANC-1) cells.

Recent breakthroughs in the synthesis of mesoporous silica materials with controlled particle size, morphology, and porosity, along with their chemical stability, has made silica matrices highly attractive as the structural basis for a wide variety of nanotechnological applications such as adsorption, catalysis, sensing, and separation. In addition, we and others have discovered that surface-fu...

In this article, mercapto-functionalized helical mesoporous silica nanorods have been synthesized by a one-step co-condensation of tetraethoxysilane (TEOS) and 3-mercaptopropyltrimethoxysilane (MPTS) using cetyltrimethylammonium bromide (CTAB) as a template. Process parameters, including MPTS concentration, stirring time and added volume of ethanol as co-solvent, were both carefully and accurat...