The number of sperm incorporated into eggs made polyspermic with varying concentrations of nicotine (0.025-0.25%, v/v) appears to be directly related to the concentrations employed. The cortical response is morphologically equivalent to that observed in control preparations. Shortly after their incorporation all of the spermatozoa undergo structural events normally associated with the developme...

Mobile apps are increasingly realized by using a crossplatform development framework. Using such frameworks, code is written once but the app can be deployed to multiple platforms. Despite progress in research on cross-platform techniques, results (i.e. apps) are not always satisfactory. They are subject to tedious tailoring and the development effort tends to be notable. In these cases, either...

We studied the distribution of parvalbumin-immunoreactive cell bodies and fibers in the cat brain stem. A high or moderate density of perikarya containing parvalbumin was observed in the periaqueductal gray, interpeduncular nucleus, nucleus of the trapezoid body, superior and inferior colliculi, and in the substantia nigra. The nucleus ruber, cuneiform nucleus, preolivary nucleus, retrorubral n...

Cells actively position their nucleus within the cytoplasm. One striking example is observed during skeletal myogenesis. Differentiated myoblasts fuse to form a multinucleated myotube with nuclei positioned in the centre of the syncytium by an unknown mechanism. Here, we describe that the nucleus of a myoblast moves rapidly after fusion towards the central myotube nuclei. This movement is drive...

Clinical observations have long indicated a vestibular influence on autonomic function. Neuroanatomical studies in the rabbit and in the cat have identified descending vestibulo-autonomic pathways from the caudal portion of the medial vestibular nucleus and the inferior vestibular nucleus to the dorsal motor nucleus of the vagus nerve, the nucleus of the solitary tract, and some brain stem medu...

The distribution of adrenocorticotropin hormone/corticotropin-like intermediate lobe peptide was studied in the cat brain stem, using an indirect immunoperoxidase technique. No immunoreactive cell bodies were observed. However, a high density of immunoreactive fibers was found in the periaqueductal gray, the dorsal nucleus of the raphe, the locus coeruleus, and the marginal nucleus of the brach...

While the parabrachial/Kölliker-Fuse complex has been described in a variety of animal species it has not been characterized in human brainstem. In the present study we investigated fetal and infant brainstems, focusing particularly on the dorsolateral part of the pontine tegmentum, with the aim of defining the precise cytoarchitecture of the medial parabrachial, lateral parabrachial, and Kölli...

It is easy to forget that less than 100 years ago, no one knew the process by which stars produce light. Today, we understand quite well that stars, which are composed mostly of hydrogen, produce energy by nuclear fusion. The enormous pressure created by the mass of a star causes pairs of hydrogen nuclei in its core to fuse into a helium nucleus thereby converting a small amount of mass into en...

Using retrograde transport of the fluorescent dye Evans Blue (EB), in combination with glyoxylic acid histofluorescence, the ponto-spinal catecholaminergic pathways were investigated. The cells which contain catecholamine and project to the lumbar spinal cord of the cat are most densely concentrated in the Kölliker-Fuse nucleus. Locus coeruleus, the subcoeruleus area, and the parabrachial nucle...