The CP violation observables S and C in the decay channel B^{0}→D^{+}D^{-} are determined from a sample of proton-proton collisions at center-of-mass energies of 7 and 8 TeV, collected by the LHCb experiment and corresponding to an integrated luminosity of 3  fb^{-1}. The observable S describes CP violation in the interference between mixing and the decay amplitude, and C parametrizes direct CP...

Cataloging the association of transcripts to genetic variants in recent years holds the promise for functional dissection of regulatory structure of human transcription. Here, we present a novel approach, which aims at elucidating the joint relationships between transcripts and single-nucleotide polymorphisms (SNPs). This entails detection and analysis of modules of transcripts, each weakly ass...

HeteroGenome is a non-redundant catalog of DNA periodicity regions in a number of complete genomes of various organisms. It shows the results of an automated spectral-statistical approach to the genome-wide heterogeneity (latent periodicity) search. The significance level of revealed heterogeneities is 10 -6 and below. Heterogeneity regions listed in the database are potential regions of a late...

Environment has long been known to play an important part in disease etiology. However, not many genome-wide association studies take environmental factors into consideration. There is also a need for new methods to identify the gene-environment interactions. In this study, we propose a 2-step approach incorporating an influence measure that capturespure gene-environment effect. We found that p...

Recently developed hybridization technology (Drmanac et al. 1994) enables economical large-scale detection of short oligomers within DNA fragments. The newly developed recognition method (Milosavljević 1995b) enables comparison of lists of oligomers detected within DNA fragments against known DNA sequences. We here describe an experiment involving a set of 4,513 distinct genomic E.coli clones o...

We compare four different risk-taking propensity measures on their ability to describe and to predict actual risky behavior in the domain of health. The risk-taking propensity measures we compare are: (1) a general measure of risk-taking propensity derived from a one-item survey question (Dohmen et al., 2011), (2) a risk aversion index calculated from a set of incentivized monetary gambles (Hol...

in this paper, we construct two fuzzy sets using the notions of level subsets and strong level subsets of a given fuzzy set in a ring r. these fuzzy sets turn out to be identical and provide a universal construction of a fuzzy ideal generated by a given fuzzy set in a ring. using this construction and employing the technique of strong level subsets, we provide the shortest and direct fuzzy set ...

The Wadden Sea is an almost untouched area with a size of about 7300 km along the German, Dutch and Danish coast. Because of tide the area is flooded two times a day, creating a very special and sensitive ecosystem. In order to protect the Wadden Sea up-todate Digital Terrain Models (DTM) of high accuracy are needed to detect morphological changes. Lidar is an adequate method to obtain an accur...

Genomic DNA is fragmented into segments using the Jensen-Shannon divergence. Use of this criterion results in the fragments being entropically homogeneous to within a predefined level of statistical significance. Application of this procedure is made to complete genomes of organisms from archaebacteria, eubacteria, and eukaryotes. The distribution of fragment lengths in bacterial and primitive ...

We extend the idea of process capability plots from the case of two-sided specification intervals to derive a graphical method useful when doing capability analysis having one-sided specification limits. The derived process capability plots are based on existing capability indices for one-sided specification limits. Both the cases with and without a target value are investigated. Under the assu...