Gastroesophageal reflux disease (GERD) is widely associated with asthma, chronic cough, and laryngitis. Many studies have focused on acidic reflux; however, acid is just one of many factors that can cause pulmonary injury. The discrepancy between the high frequency of GERD in asthmatic patients and the ineffective reflux therapy outcomes in these patients suggests that GERD may cause injury thr...

Volume 89, Number 5 www.aafp.org/afp American Family Physician 395 The American Academy of Pediatrics (AAP) has published a guideline on the management of gastroesophageal reflux (GER) in children based on recommendations from the North American and European Societies for Pediatric Gastroenterology, Hepatology, and Nutrition. It is important to determine whether the patient has gastroesophageal...

This article deals with the problem of gastroesophageal reflux disease (GERD) in children, which has an enormous medical and social importance. Despite recent advances in therapy, the disease is characterized by recurrent exacerbations with the development of complications, which dictates the need of finding a new pathogenically supported esophagitis treatment. In this regard, the effectiveness...

Up to 40% of patients with gastroesophageal reflux disease (GERD) suffer from proton pump inhibitor refractory GERD but clinically the medications to strengthen the OPEN ACCESS Molecules 2015, 2

Gastroesophageal reflux disease (GERD) is a chronic on spectrum that has an array of management options ranging from lifestyle changes, acid suppressive therapy to laparoscopic anti-reflux surgery (LARS). Transoral incisionless fundoplication (TIF) endoscopic procedure in the GERD re-establishes and augments gastroesophageal flap valve (GEFV). TIF appropriate for patients do not have hiatal her...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1853 with no underlying systemic abnormalities. GER is a common condition involving regurgitation, or “spitting up,” which is the passive return of gastric contents retrograde into the esophagus. The prevalence of GER peaks between one to four months of age, and usually resolves by six to 12 months of age. No gender predilection or definite peak age of...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1853 with no underlying systemic abnormalities. GER is a common condition involving regurgitation, or “spitting up,” which is the passive return of gastric contents retrograde into the esophagus. The prevalence of GER peaks between one to four months of age, and usually resolves by six to 12 months of age. No gender predilection or definite peak age of...

Gastroesophageal reflux disease (GERD) is a chronic, progressive, and costly medical condition affecting a substantial proportion of the world population, predominantly the Western population. The available treatment options for patients with refractory GERD symptoms are limited to either laparoscopic surgery with significant sequelae or potentially lifelong, high-dose proton pump inhibitor the...

Gastroesophageal reflux disease (GERD) and GERD-related symptoms are common, and affect 25% to 30% of the general population. Upper gastrointestinal endoscopy of the esophagus has been the most widely used modality for the diagnosis and grading of reflux disease. Endoscopic imaging today has evolved beyond the confines of routine white light endoscopy (WLE) to advanced optical imaging with a pr...

OBJECTIVES To critically review and summarize the literature on cough and gastroesophageal reflux disease (GERD), and to make evidence-based recommendations regarding the diagnosis and treatment of chronic cough due to GERD. DESIGN/METHODOLOGY Ovid MEDLINE literature review (through March 2004) for all studies published in the English language and selected articles published in other language...