نتایج جستجو برای: gene delivery polyethyleneimine

تعداد نتایج: 1325684  

Journal: :journal of paramedical sciences 0
afshin khavari department of hepatitis and aids, pasteur institute of iran, tehran, iran zahra orafa department of hepatitis and aids, pasteur institute of iran, tehran, iran mehrdad hashemi department of genetics, islamic azad university, tehran medical sciences branch,tehran,iran noorieh habibzadeh department of hepatitis and aids, pasteur institute of iran, tehran, iran azam bolhassani department of hepatitis and aids, pasteur institute of iran, tehran, iran

delivery of exogenous materials such as nucleic acids, peptides, proteins, and drugs into cells is an important strategy in modern cellular and molecular biology. recently, the development of gene carriers for efficient gene transfer into cells has attracted a great attention. furthermore, lack of effective drug delivery is one of the major problems of cancer chemotherapy. many physical methods...

2011
Hamid Reza Samadikhah Asia Majidi Maryam Nikkhah Saman Hosseinkhani

PURPOSE Cationic liposomes (CLs) are composed of phospholipid bilayers. One of the most important applications of these particles is in drug and gene delivery. However, using CLs to deliver therapeutic nucleic acids and drugs to target organs has some problems, including low transfection efficiency in vivo. The aim of this study was to develop novel CLs containing magnetite to overcome the defi...

Journal: :BMC Biotechnology 2009
Shuai Shi QingFa Guo Bing Kan ShaoZhi Fu XiuHong Wang ChangYang Gong HongXin Deng Feng Luo Xia Zhao YuQuan Wei ZhiYong Qian

BACKGROUND Polyethyleneimine (PEI), a cationic polymer, is one of the successful and widely used vectors for non-viral gene transfection in vitro. However, its in vivo application was greatly limited due to its high cytotoxicity and short duration of gene expression. To improve its biocompatibility and transfection efficiency, PEI has been modified with PEG, folic acid, and chloroquine in order...

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