نتایج جستجو برای: gene set analysis
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Although techniques of chromatin immunoprecipitation coupled with high throughput sequencing (ChIP-seq) or tiling array hybridization (ChIP-chip) have came into being for a long time, it still remains difficult to generate a quality ChIPx (i.e., ChIP-seq or ChIP-chip) data set due to the tremendous amount of effort required to develop effective antibodies and efficient protocols. Especially wit...
Gene-set analysis aims to identify differentially expressed gene sets (pathways) by a phenotype in DNA microarray studies. We review here important methodological aspects of gene-set analysis and illustrate them with varying performance of several methods proposed in the literature. We emphasize the importance of distinguishing between 'self-contained' versus 'competitive' methods, following Go...
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