background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

introduction: central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. we described an un-usual case of a 22-year-old man with idi-opathic ...

central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.multifocal cgcgs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as noonan-like multiple giant cell lesion syndrome or other disorders.very few c...

Background: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. Giant cell tumor (GCT) of the sphenoid bone is relatively rare. In this report, we describe a tumor of the greater wing of left sphenoid bone. Case presentation: A 31-year-old female was presented with headache, proptosis and diplopia of her left eye. Cranial magnetic resonance ima...

Thymic epithelial neoplasms are commonly aetiology of the anterior mediastinum masses in adults. It represents 20–30% of all mediastinal tumours in adults. Ectopic thymomas usually affect the neck, mediastinal compartments, lung, and pleura, arising from aberrant thymic tissue. For giant thymoma, there is still no consensus on the surgical approach.  We herein report a patient with a giant thym...

objective: oral lesions are among the important reasons for seeking dental care. being frequently encountered, giant cell lesions form an important group of oral lesions. the epidemiologic data on these lesions, however, is scarce in iran. the present study investigated epidemiological and demographic characteristics of giant cell lesions in oral biopsies done in one of the largest oral patholo...

  Two rare cases of extra-articular diffuse variant giant cell tumor of the tendon sheath are presented, at the elbow of a 68-year-old female and the foot of a 56-year-old male. Both patients presented with a palpable masses and marginal excision was performed; histological sections confirmed the diagnosis of extra-articular giant cell tumor. No adjuvant therapy was administered. At the last fo...

phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. while the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors greater than ten centimetres in diameter – the giant phyllodes tumor. we report a case of giant breast tumors and discuss the techniques utilized for pre-operat...