Introduction Quality control (QC) protocols are now routinely used on clinical Magnetic Resonance Imaging (MRI) devices. Most of the time, these QC procedures are manufacturer-specific, and then not useable for multicenter projects involving multiple MRI systems from different vendors on different sites. The aim of the work package 1 of the Grand Ouest Glioblastoma Project (GOGP) [1], a multice...

Malignant transformation is reported in less than 2% of benign cystic teratomas. Although all the elements can undergo this transformation, it is most often seen in squamous epithelium. The malignancy of neural elements is probably the least common event, with only one case previously reported. A case of glioblastoma multiform in a benign cystic teratoma is presented. Its neural derivation was ...

Primary and secondary malignant central nervous system (CNS) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. Glioblastoma multiform (GBM), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced DNA damage repair program that also induces recurrence and resists current chemo- and radio...

Glioblastoma or glioblastoma multiform (GBM), is recognized as the most frequent and malignant nervous system tumor. Conventional therapeutic strategies, such as surgical resection and chemo-radiotherapy, have done very little in prolonging the survival time of GBM patients. The difficulties in human GBM therapy are due to the inherently complicated pathological characteristic and numerous drug...

Gliomablastoma multiform (GBM) is the most fatal form of all brain cancers in humans. Currently there are limited diagnostic tools for GBM detection. Here, we applied surprisal analysis, a theory grounded in thermodynamics, to unveil how biomolecule energetics, specifically a redistribution of free energy amongst microRNAs (miRNAs), results in a system deviating from a non-cancer state to the G...

Radiomics is a term which refers to the analysis of the large amount of quantitative tumor features extracted from medical images to find useful predictive, diagnostic or prognostic information. Many recent studies have proved that radiomics can offer a lot of useful information that physicians cannot extract from the medical images and can be associated with other information like gene or prot...

Imaging is essential for evaluating patients with glioblastoma. Traditionally a multimodality undertaking, CT, including CT cerebral blood profusion, PET/CT traditional fluorine-18 fluorodeoxyglucose (18F-FDG), and MRI have been the mainstays diagnosis post-therapeutic assessment. However, recent advances in these modalities, league emerging fields of radiomics theranostics, may prove helpful i...