To assess mechanisms for postprandial hyperglycemia, we used a triple-isotope technique ([\3-(3)H]glucose and [(14)C]bicarbonate and oral [6,6-dideutero]glucose iv) and indirect calorimetry to compare components of glucose release and pathways for glucose disposal in 26 subjects with type 2 diabetes and 15 age-, weight-, and sex-matched normal volunteers after a standard meal. The results were ...

The plasma glucose excursion may influence the metabolic responses after oral glucose ingestion. Although previous studies addressed the effects of hyperglycemia in conditions of hyperinsulinemia, it has not been evaluated whether the route of glucose administration (oral vs. intravenous) plays a role. Our aim was to determine the effects of moderately controlled hyperglycemia on glucose metabo...

plants with hypoglycemic properties are important in the treatment of diabetes. one of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. the aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of iran and their effects on glucose diffusion decrease. the amounts of phenolic co...

results coincubation of islets with vitamin d (10 nm) and 11.1 mm glucose increased islet insulin release (37.27 ± 3.75 vs. 24.64 ± 2.83 ng/islet/24 hours; p < 0.05), while vitamin d (1 and 10 nm) decreased insulin release in the presence of 16.7 mm glucose (21.14 ± 3.58 and 18.65 ± 3.84 vs. 37.71 ± 4.63 ng/ islet/24 hours; p < 0.05). islets preincubation with vitamin d (1 and 10 nm) increased ...

In recent decades, rates of insulin resistance and hypertension increase dramatically due to many factors. One them is excessive fructose consumption. P-coumaric acid has potent antioxidant anti hyperglycemic properties. Aim the work: this study, we examined ability p-coumaric prevent high induced possible underlying mechanisms. Material methods: 24 adult male albino rats were divided randomly ...

Although hypoglycemia and hyperglycemia are common in patients the intensive care unit (ICU) may negatively impact treatment outcomes, glycemic variability has recently gained attention as a promising risk factor these patients. This study investigated of hypoglycemia, on outcomes ICU Daily blood glucose levels measured for participants were classified within reference range 110–180 mg/dL or ou...

OBJECTIVE To assess the contribution of decreased glucose clearance to the rise in fasting plasma glucose (FPG) in the nondiabetic range. RESEARCH DESIGN AND METHODS A total of 120 subjects with normal glucose tolerance received an oral glucose tolerance test and euglycemic insulin clamp with 3-[(3)H]glucose. The basal and insulin-stimulated rates of glucose appearance, glucose disappearance,...

abstract background and objective: diabetes mellitus is one of complications that thalassemia major patients face with. hence, blood glucose monitoring is of vital importance to these patients. because of high level of fetal hemoglobin in these patients, the measurement of hemoglobin a1c is not reliable and should be displaced by fructosamine test. material and methods: the current descriptive ...

objective: type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. chromium (cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in iran. the aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, hba1c, lipid profile and lipid peroxidation in type 2 diab...