Acrylamide (AC) is a noxious chemical and it is widely used in this modernized world. There by this study aimedto assess the acrylamide induced neurotoxicity and genotoxicityonmale wistar rat brain. Based on the study aim, male at brainwas exposed by short term and long term to acrylamide and investigated the crucial changes in glutathione S-transferases and its associated glutathione peroxidas...

A monoclonal antibody has been produced in the mouse system using purified rat liver ligandin as antigen. The antibody is of the immunoglobulin M class and appears to be specific for the Ya subunit of lowest molecular weight which comprises the isoenzymes of glutathione S-transferases in rat liver. Of the series of glutathione S-transferases, the antibody cross-reacted with purified ligandin (Y...

We have characterized a Drosophila glutathione S-transferase (RX:glutathione R-transferase, EC 2.5.1.18) cDNA encoding a protein of 209 amino acids. The cDNA was expressed in Escherichia coli harboring the expression plasmid construct pGTDml-KK. The active enzyme, designated as Drosophila glutathione S-transferase 1-1, had a specific activity toward 1-chloro-2,4-dinitrobenzene comparable to tha...