OBJECTIVE To compare long GnRH agonist with GnRH antagonist protocol in poor responders. MATERIALS AND METHODS Medical charts of 531 poor responder women undergoing in-vitro fertilization (IVF) cycle at Zeynep Kamil Maternity and Children's Hospital, IVF Center were retrospectively analysed. Those who received at least 300 IU/daily gonadotropin and had ≤3 oocytes retrieved were enrolled in th...

BACKGROUND GnRH agonist and antagonist were developed to control the premature release of LH surge. There is some difference between two protocols. OBJECTIVE We compared the outcome of frozen-thawed embryo transfer in infertile women who used GnRH agonist or antagonist protocol for previous COH cycle and evaluation of any adverse effect of GnRH antagonist on oocyte and embryo. MATERIALS AND...

To determine the effect of estrogen and progesterone on plasma volume (PV) and extracellular fluid volume (ECFV), we suppressed endogenous estrogen and progesterone by using the gonadotropin-releasing hormone (GnRH) antagonist ganirelix acetate in seven healthy women (22 +/- 1 yr). Subjects were administered GnRH antagonist for 16 days. Beginning on day 5 of GnRH antagonist administration, subj...

OBJECTIVE To compare antimüllerian hormone (AMH) and antral follicle count (AFC) as predictors of ovarian response to controlled ovarian stimulation at individual fertility clinics. DESIGN Retrospective analysis of individual study center data in two multicenter trials. Centers that provided >10 patients were included in the analysis. SETTING A total of 19 (n = 519 patients) and 18 study ce...

background: our objective was to evaluate the effectiveness of clomiphene citrate (cc) vs. letrozole (l) plus human menopausal gonadotropin (hmg) in gonadotropin releasing hormone (gnrh) antagonist protocol in poor prognosis women with previous failed ovarian stimulation undergoing intracytoplasmic sperm injection (icsi). materials and methods: this retrospective cohort study included cycles wi...

background: to assess the usefulness of premature luteinization hormone (lh) surge prevention in an intrauterine insemination (iui) cycle by gnrh antagonist administration materials and methods: sixty patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled in this prospective randomized controlled trial. there were twenty patients in group a (with gnrh ...

OBJECTIVE To systematically evaluate the effectiveness of the gonadotropin-releasing hormone (GnRH) antagonist on in vitro fertilisation (IVF) in patients with polycystic ovary syndrome (PCOS). METHODS Nine types of databases were searched by computer, and nine types of relevant journals were searched manually. Randomized, controlled trials of the effects of the GnRH antagonist and GnRH agoni...

OBJECTIVE To evaluate the effectiveness of GnRH antagonist multiple dose protocol applied during early and late follicular phase (MDP-EL) in comparison with standard GnRH agonist luteal long protocol (LP) in each non-obese and obese polycystic ovary syndrome (PCOS) women undergoing IVF. METHODS Two hundred eleven infertile women with PCOS were recruited and randomized to undergo either GnRH a...

BACKGROUND We aimed to assess the efficacy of a GnRH antagonist in intrauterine insemination (IUI) cycles to increase number of mature ovulatory follicles and pregnancy rates. METHODS Prospective randomized study. Women (18-38 years old) with primary/secondary infertility were included. Eighty-two patients were randomly assigned to controlled ovarian stimulation (COS) consisting of rFSH + GnR...

background: gnrh agonist administration in the luteal phase has been suggested to beneficially affect the outcome of intracytoplasmic sperm injection (icsi) and embryo transfer (et) cycles. this blind randomized controlled study evaluates the effect of gnrh (gonadotropine releasing hormone) agonist administration on icsi outcome in gnrh antagonist ovarian stimulation protocol in women with 2 or...