Gonadotropin-inhibitory hormone (GnIH) is a novel hypothalamic neuropeptide that was discovered in quail as an inhibitory factor for gonadotropin release. GnIH inhibits gonadotropin synthesis and release in birds through actions on gonadotropin-releasing hormone (GnRH) neurons and gonadotropes, mediated via the GnIH receptor (GnIH-R), GPR147. Subsequently, GnIH was identified in mammals and oth...

gonadotropin releasing hormone (gnrh) plays a key role in reproduction. this decapeptide is synthesized and released by hypothalamus and induces the pituitary gonadotrop cells to release pituitary gonadotropin hormones. in some extrapituitary compartments gnrh and its receptor act as part of the autocrine regulatory system of cell proliferation. the anticancer activity of gnrh and its analogues...

We investigated the differences in the expression of the neurohormones kisspeptin (Kiss) and gonadotropin-inhibitory hormone (GnIH) and cytochrome P450 aromatase (P450arom), gonadotropin hormones (GTHs), and sex steroids in the goldfish Carassius auratus exposed to light-emitting diodes (LEDs). The expression levels of Kiss1, Kiss2, G-protein-coupled receptor 54 (GPR54), GTHs, GnIH, and P450aro...

Objective(s): To benefit from reproduction and deal with challenges in the environmental conditions, animals must adapt internal physiology to maximize the reproduction rate. Maladaptive variations in the neurochemical systems and reproductive system can lead to manifestation of several significant mammalian reprocesses, including mammalian ovarian lifespan. RFamide-related peptide (RFRP, Rfrp)...

Tsai, Shiow-Chwen, Chien-Chen Lu, Jiann-Jong Chen, Yu-Chung Chiao, Shyi-Wu Wang, Jiuan-Jiuan Hwang, and Paulus S. Wang. Inhibition of salmon calcitonin on secretion of progesterone and GnRH-stimulated pituitary luteinizing hormone. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E49–E55, 1999.—The effects of salmon calcitonin (sCT) on the production of progesterone and secretion of luteinizing hor...