BACKGROUND All published studies of health care utilization in gout have been cross-sectional to date, and most used a patient-reported diagnosis of gout. Our objective was to assess health care utilization and its predictors in patients with physician-confirmed gout in a prospective cohort study. METHODS In a multi-center prospective cohort study of U.S. veterans with rheumatologist-confirme...

BACKGROUND To characterize the differences between women and men with gout. METHODS We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Ri...

If left untreated, gout may result in radiographic abnormalities, that is, cartilage loss and periarticular osteopenia plus more-or-less gout-specific radiographic abnormalities: spurs, sclerosis, and periostal new bone formation. In the current issue, Dalbeth and colleagues describe findings from about 800 joints in 20 mostly tophaceous patients, which can help clinicians to identify osteopath...

BACKGROUND Comorbidities are common in patients with gout, yet qualitative research is lacking. The study objective was to examine the impact of gout on comorbidities. METHODS Nine nominal groups were conducted. Patients with gout discussed and rank-ordered their concerns in response to the question, "How does gout or its treatment affect your other conditions and their treatment?" RESULTS ...

BACKGROUND Patient satisfaction with treatment directly impacts adherence to medication. OBJECTIVE The objective was to assess and compare treatment satisfaction with the Treatment Satisfaction Questionnaire for Medication (TSQM), gout-specific health-related quality of life (HRQoL) with the Gout Impact Scale (GIS), and generic HRQoL with the SF-12v2(®) Health Survey (SF-12) in patients with ...

• The concept of a fungalImycotoxin etiology of gout/ hyperuricemia in humans was first reported by Costantini (1989) (1). Gout and/or hyperuricemia have been induced in animals by the fungal species Ustilago maydis, Chaetomium trilaterale, Saccharomyces cerversiae, and by the mycotoxins, aflatox'm, ochratoxin, oosporein, oxalic acid. Gout and/or hyperuricemia have been induced in humans by the...

To determine the prevalence of hyperuricaemia, gout and gout-related factors in Central Taiwan Atayal aborigines, 342 subjects over 18 yr old were interviewed and examined. A questionnaire was designed to screen for signs and symptoms of gout and gout-related risk factors. Serum uric acid, triglyceride and creatinine were measured in all subjects. The prevalence of hyperuricaemia was 41.4% and ...

To editor, Gout is a common rheumatological disease caused by a disturbance in uric acid metabolism. Tophi develop during most advanced clinical stage of gout, and usually present as firm pink nodules or fusiform swelling, mainly at periarticular sites. However, unusual skin manifestations caused by intradermal and subcutaneous deposition of tophaceous material at locations other than periartic...

INTRODUCTION The incidence of gout in broiler birds has been speculatively blamed on the high protein levels in diets. Gout in birds can be in two forms, visceral gout and articular gout. Visceral gout is the most common form in poultry, wherein the plasma uric acid levels are high and urates are deposited in the visceral organs. Sillers (1959) suggested that this form of gout is the result of ...

Patients with gout are more likely to develop most cancers than subjects without gout. Colchicine has been used for the treatment and prevention of gouty arthritis and has been reported to have an anticancer effect in vitro. However, to date no study has evaluated the relationship between colchicine use and incident cancers in patients with gout. This study enrolled male patients with gout iden...