Glucocorticoid remediable aldosteronism (GRA) is rare familial form of primary aldosteronism characterized by a normalization of hypertension with the administration of glucocorticoids. We present a case of GRA and thoracoabdominal aneurysm complicated by multiple aortic dissections requiring complex surgical and endovascular repairs. Registry studies have shown a high rate of intracranial aneu...

the purpose of the present study was to explore the passive and electrically assisted transdermal transport of granisetron hydrochloride (gra) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. in this study, iontophoretic permeation of gra through guinea pig skin...

Cytolytic granule-mediated target cell killing is effected in part through synergistic action of the membrane-acting protein perforin and serine proteases such as granzymes A (GrA) or B (GrB). In the present study we examine GrA cellular entry and nuclear uptake in intact mouse myeloid FDC-P1 cells exposed to perforin using confocal laser scanning microscopy, as well as reconstitute GrA nuclear...

     The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...

Generic Router Assist (GRA) is a network-based service that enables end-to-end multicast transport protocols to take advantage of information distributed across the network elements in a given multicast distribution tree. The service consists of a canonical set of simple functions which network elements may apply to selected packets in the transport session as they traverse the distribution tre...

Taiwan is affected by three primary types of natural disaster: typhoons, earthquakes, and floods. Natural disasters in Taiwan can cause human causalities and loss of housing. Therefore, a method for evaluating the severity of losses caused by natural disasters would be beneficial for disaster management institutes in Taiwan when developing further supply chain management (SCM) strategies. To ev...

Abstract Accurate identification of fault source causing voltage sag is great significance to the governance and further research sag. In this paper, a method based on improved grey correlation analysis (GRA) proposed. view deficiency that traditional GRA only considers similarity, proposed geometric area slope sequence into calculation coefficient, so has attributes both similarity data closen...

Staphylococcus aureus is a major pathogen in humans and causes serious problems due to antibiotic resistance. We investigated the antimicrobial effect of glycyrrhetinic acid (GRA) and its derivatives against 50 clinical S. aureus strains, including 18 methicillin-resistant strains. The minimum inhibitory concentrations (MICs) of GRA, dipotassium glycyrrhizate, disodium succinoyl glycyrrhetinate...