An extract of fenugreek (Trigonella foenum graecum) seeds was isolated and evaluated for antioxidant activity using various in vitro assay systems. The seed extract exhibited scavenging of hydroxyl radicals ( OH) and inhibition of hydrogen peroxide-induced lipid peroxidation in rat liver mitochondria. The OH scavenging activity of the extract was evaluated by pulse radiolysis and the deoxyribos...

Comparative efficacy of two indigenous herbal extracts, (Trigonella foenum-graecum seed & Coccinia indica leaves) with the commonly used drug Glimepiride were studied. Healthy young rats (n=30) of both sexes weighting between 150 to 200 gm were selected and divided into six equal groups, as A (Control), B (diabetic), experimental diabetic groups wereC, D, E and F, treated with combined extract ...

Trigonella foenum-graecum (Fabaceae) is a medicinal plant. It is traditionally used in the treatment and prevention of several ailments. Pharmacological investigations showed anti-bacterial, anti-diabetic, anticancer, anti-diarrheal, anti-inflammatory activities. Phytochemical analysis showed the presence of quinone, flavones, flavonoids, phenols, tannins, terpenoids, lactones, alkaloids and po...

Methanol extracts from 27 medicinal plant species were tested at concentrations of 0.5, 1 and 2 mg/mL for their in vivo fungicidal activities against six phytopathogenic fungi. Their efficacy varied with plant pathogen, tissue sampled and plant species. Very strong fungicidal activity was produced by extracts of Boswellia carterii, Saussurea lappa, Glycyrrhiza uralensis, Piper nigrum, Rheum cor...

Thiosemicarbazides have found to contain antimicrobial, antiviral activities against various virus, bacteria and fungi strains. The objective of the study was to study the seed germination and physiological maturity stage of Trigonella foenum graecum and Brassica (L.). The effect of various concentrations of 1γ picolinoyl-4-phenyl Thiosemicarbazides on mitotic Indices in root tip cell in Trigon...

Trigonella foenum-graecum and Zingiber officinale are used as traditional medicinal plants for the treatment of infectious inflammatory diseases. However, a comparative analysis bioactivities T. Z. lack some necessary information therapeutic purposes. This study was designed to evaluate biochemical characterizations biological efficacy antioxidant, antidiabetic, antiamnesic, cytotoxic agents. A...

Objective- This study was performed to evaluate whether Trigonella foenum graecum (fenugreek) seeds extract has any protective activity in intestinal ischemia/reperfusion injury in rat. Design- Experimental study. Animals- 20 male Wistar albino rats. Procedures- Four groups of rats were included in this study. Group I (I/R) underwent ischemia-reperfusion (I/R) of the intestine (45 min of isc...

Diabetes is an oxidative stress disorder and oxidative damage to tissues such as heart, kidney, liver and other organs may be a contributory factor to several diabetic complications. Momordica charantia (family: Cucurbitaceae) and Trigonella foenum graecum (family: Fabaceae) are used traditionally in Indian folk medicine to manage diabetes mellitus. In the present study, the anti-hyperglycemic ...

Trigonella foenum graecum commonly known as Fenugreek exerts normoglycemic and insulinotropic effects in humans by compounds from its seed and leaf extracts. Some studies reported that treating pregnant mice with fenugreek seed could cause toxic effects on the nervous system of its pubs during developmental growth, while in some other studies neuroprotective properties were considered for it. S...