Vegetable oils are a class of natural products very frequently used in phytocosmetology. Natural remedies with antiaging action are very popular in our days. Harmfulness of natural compounds on the skin, is quickly observed by the 24-48 hour patch test skin irritation and erythema measurement. Changes in the concentration of melanin and sebum in the dermis, represent real parameters which give ...

Grape seed extract (GSE) is one of Japan's natural food additives, and is recommended for use as an antioxidant. The component of interest is polyphenol, mainly proanthocyanidins, which are condensed tannins. A vanillin-hydrochloric acid (HCl) assay is specific for flavan-3-ol. The sensitivity of GSE components to the vanillin-HCl assay differed according to the chemical structure. We applied t...

The skins and seeds of grapes are known to be rich sources of phenolic compounds, both flavonoids and non-flavonoids. The aim of the present study is to determine polyphenolic composition, antioxidant potential along with free radical scavenging activity and antimicrobial properties of ethanol extract of Grape skin and seed. Grape seed showed high antioxidant and antimicrobial activity compared...

OBJECTIVE Mucositis is a serious disorder of the gastrointestinal tract that results from cancer chemotherapy. We investigated the effects of increasing grape seed extract doses on the severity of chemotherapy in a rat model and its coincident impact on chemotherapeutic effectiveness in colon cancer cells. DESIGN Female Dark Agouti rats were gavaged with grape seed extract (400-1000 mg/kg) or...

Degradation of nutraceuticals in low- and intermediate-moisture foods heated at high temperature (>100 degrees C) is difficult to model because of the nonisothermal condition. Isothermal experiments above 100 degrees C are difficult to design because they require high pressure and small sample size in sealed containers. Therefore, a nonisothermal method was developed to estimate the thermal deg...

UNLABELLED Grape juice processing by-products, grape seed and pomace are a rich source of procyanidins, compounds that may afford protection against chronic disease. This study was undertaken to identify optimal extrusion conditions to enhance the contents of monomers and dimers at the expense of large molecular weight procyanidin oligomers and polymers in grape seed and pomace. Extrusion varia...

Polyphenol-rich grape seeds have a beneficial effect on human health. The present study was performed to investigate the effects of grape seeds on antioxidant activities in rats. Male Sprague-Dawley rats were randomly divided into a control diet group (C), a high-fat diet group (HF), a 5% grape seed-supplemented control diet group (G), and a 5% grape seed-supplemented high-fat diet group (HG). ...

Grape pomace (pulp and skins) was investigated as a new biosorbent for removing mycotoxins from liquid media. In vitro adsorption experiments showed that the pomace obtained from Primitivo grapes is able to sequester rapidly and simultaneously different mycotoxins. Aflatoxin B1 (AFB1) was the most adsorbed mycotoxin followed by zearalenone (ZEA), ochratoxin A (OTA), and fumonisin B1 (FB1), wher...

Grape hyacinth (Muscari spp.) is a popular ornamental bulbous perennial famous for its blue flowers. To understand the chemical basis of the rich blue colors in this plant, anthocyanin profiles of six blue flowering grape hyacinths as well as one pink and one white cultivar were determined using high-performance liquid chromatography and mass spectrometry. Along with two known compounds, eight ...

Chen, Tzu Ying. Ph.D., Purdue University, December 2013. Brain Bioavailability of Polyphenols: Implications for Delivery of Brain Health Benefits. Major Professor: Elsa M. Janle and Mario G. Ferruzzi. Consumption of fruits and vegetables has been associated with neuroprotection and cognitive benefits throughout the life span. These associations have sparked interest in plant derived polyphenols...