A case is presented in which a 4p+/17q- familial balanced reciprocal translocation in the mother produced a son with primary trisomy-21, as well as the structural chromosomal anomaly. A number of similar situations have been reported, suggesting that the two events are related. In practice, this (as well as other direct risks) should be taken into account when counseling those families in which...

Well-synchronized populations of oocytes obtained by means of the "pupal system" (Grell, 1973a) have been examined to determine the time of appearance of the synaptonemal complex. The complex first appears in the most advanced oocytes between 132 and 138 hr of female development. Between 138 and 156 hr the complex apparently undergoes a fourfold increase in length. At 150 and 156 hr the complex...

N the strain of Drosophila known as “red fat cells” conspicuous pigmented Icells are visible in the head and thorax of the flies (JONES and LEWIS 1957). Normally colorless fat cells acquire a pigment that is related to, or perhaps identical with, the brown ommochrome derived from tryptophan. This report concerns some properties of the red fat cells (RFC) strain, two of which have been briefly r...

TURTEVANT estimated that the total number of spontaneous fourth-chromosome crossovers detected from diploid females up to 1951 was less than five. The linkage map of the chromosome that he published at that time was based on studies of diplo-IV triploids, where an appreciable amount of exchange occurs (MORGAN, STURTEVANT and MORGAN 1945). The present paper describes a method for inducing recomb...

AFFILIATIONS: DABBERDT—Vaisala, Boulder, Colorado; CARROLL— University of Michigan, Ann Arbor, Michigan; BAUMGARDNER— Universidad Nacional Autónoma de México, Mexico City, Mexico; CARMICHAEL—University of Iowa, Iowa City, Iowa; COHEN— University of California—Berkeley, Berkeley, California; DYE— Sonoma Technology Inc., Petaluma, California; ELLIS—Lawrence Livermore National Laboratory, Livermor...

The 1-methyl-nicotinamide radical (MNA(*)), produced by pulse radiolysis has previously been shown to reduce the Cu(A)-site of cytochromes aa(3), a process followed by intramolecular electron transfer (ET) to the heme a but not to the heme a(3) [Farver, O., Grell, E., Ludwig, B., Michel, H. and Pecht, I. (2006) Rates and equilibrium of CuA to heme a electron transfer in Paracoccus denitrificans...