Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Aryayev M, Senkivska L. Growth response, psychosocial problems, and quality of life in children with growth hormone deficiency. Pediatria Polska - Polish Journal Paediatrics. 2022;97(3):236-241. doi:10.5114/polp.2022.120074. APA Aryayev, M., & Senkivska, (2022). Paediatrics, 97(3), 236-241. https://doi.org/10.5114...

A girl with the Cohen syndrome and isolated growth hormone deficiency is described. Treatment with biosynthetic human growth hormone resulted in marked catch up growth to normal stature. It is concluded that growth hormone deficiency should be ruled out in patients with the Cohen syndrome and small stature.

OBJECTIVE To investigate the incidence and severity of pituitary insufficiency after aneurysmal subarachnoid haemorrhage. METHODS Pituitary function was tested in a series of patients more than 12 months but less than 60 months after aneurysmal subarachnoid haemorrhage using a combined TRH-LHRH-arginine test and the insulin tolerance test, to elucidate possible deficits in the gonadotrophic, ...

Lacey, K. A., Hewison, A., and Parlin, J. M. (1973). Archives of Disease in Childhood, 48,508. Exercise as a screening test for growth hormone deficiency in children. The serum growth hormone response to exercise has been evaluated in 98 children with short stature. In 65 children growth hormone deficiency was excluded by a single postexercise level of more than 20 mIU/ml. The test is simple an...

1. In adult humans with growth hormone deficiency, treatment with growth hormone has recently been shown to have major anabolic effects and to improve exercise performance. The cardiovascular effects of growth hormone in adults with growth hormone deficiency were examined in 24 patients treated with recombinant human growth hormone (0.07 units/kg at night) in a double-blind, placebo-controlled ...

Brief Summary: This study extends the phenotypes related to pathogenic biallelic RNPC3 variants cover primary ovarian insufficiency (POI) in combination with previously associated growth hormone deficiency (GHD).