Bile acids (BAs) act as signaling molecules in various physiological processes, and are related to colonic microbiota composition as well as to different types of dietary fat and fiber. This study investigated whether guar gum and pectin-two fibers with distinct functional characteristics-affect BA profiles, microbiota composition, and gut metabolites in rats. Low- (LM) or high-methoxylated (HM...

Six non-anaesthetized Large White pigs (mean body weight 59 +/- 1.7 kg) were fitted with permanent catheters in the portal vein, the brachiocephalic artery and the right hepatic vein and with electromagnetic flow probes around the portal vein and the hepatic artery. The animals were provided a basal none-fibre diet (diet A) alone or together with 6% guar gum (diet B) or 15% purified cellulose (...

Two experiments were conducted to evaluate the effects of a commercial endo-β-D-mannanase (Hemicell) on overall performance, MEn, net energy for gain, and some serum parameters of broilers fed diets varying in β-mannan level (experiment 1) and to evaluate effects of enzyme level on the same variables in broilers fed diet high in β-mannan (experiment 2). As a semipurified β-mannan source, guar g...

Biomedical evidence in the last 20 years has shown that the consumption of partially hydrolyzed guar gum may influence lipid and/or carbohydrate metabolism at many levels. Since intestine represents the first interface to interact with dietary partially hydrolyzed guar gum in vivo, we evaluated gene expression profiles in small intestinal mucosa of db/db mice fed with partially hydrolyzed guar ...

The effects of incorporating Fybogel (3.5 and 7 g doses), Metamucil (7 g) or guar gum (2.5 and 14.5 g doses) in a drink containing 50 g glucose on plasma glucose, plasma insulin and gastric emptying were studied in thirty-eight normal volunteers. In addition, the effects of Fybogel (7 g) on glucose tolerance, plasma insulin and gastric emptying were measured in fourteen non-insulin-dependent di...

The aim of present study is to exist a novel super disintegrants in fast dissolving tablet. Guar gum is a natural substance and used in many pharmaceutical product and it can also used as a super disintegrating agent in fast dissolving tablet. The result is that it released the 99.21% drug in 15min as compared to Sodium Starch Glycolate (SSG), where only 97.51% drug was released. The onset of t...

PURPOSE OF STUDY: In the present study, an attempt was made to increase therapeutic effectiveness, reduction in dosing frequency and thus improving patient compliance, by developing sustained release matrix tablets of Diclofenac sodium using guar gum as release modifier. METHOD: Six batches of sustained release matrix tablets of Diclofenac sodium was prepared by using different drug: polymer ra...

PURPOSE To determine the efficacy of the dietary fiber guar gum as a therapeutic option for reducing body weight by conducting a meta-analysis of randomized controlled trials. METHODS Literature searches were performed on the electronic databases Medline, Embase, Biosis, Amed, and the Cochrane Library. Manufacturers of commercial guar gum preparations and experts on the subject were contacted...

Polymer-clay nanocomposites are highly sought-after materials, mainly due to their applicability in a variety of avenues. From the standpoint of the preparation of these nanocomposites, however, organic compatibility with clay and adherence to "green chemistry" concepts and principles can be limiting factors. As such, the objective was to prepare a biopolymer-modified clay nanocomposite using a...

Graft copolymerization of acryl-amide onto guar-gum has been carried out in the presence of potassium per sulphate as a redox initiator. The prepared graft copolymer was characterized by various techniques such as FT-IR, SEMEDX and TGA-DTA-DTG. Activated charcoal was also studied as the adsorbent in the present study to evaluate their adsorption capacity for Cr (Vl) and compared it with indigen...