Harmful algal blooms (HABs) are a serious threat to coastal resources, causing a variety of impacts on public health, regional economies, and ecosystems. Plankton analysis is a valuable component of many HAB monitoring and research programs, but the diversity of plankton poses a problem in discriminating toxic from nontoxic species using conventional detection methods. Here we describe a sensit...

Anxiety disorders are the most prevalent central nervous system diseases imposing a high social burden to our society. Emotional processing is particularly controlled by GABA-ergic transmission in the amygdala. Using in situ hybridization and immunohistochemistry we now investigated changes in the expression of GABA synthesizing enzymes (GAD65 and GAD67), GABA(A) (α1-5, β1-3, γ1-2) and GABA(B) ...

Understanding interactions between harmful algal bloom (HAB) species and their grazers is essential for determining mechanisms of bloom proliferation and termination. We exposed the common calanoid copepod, Temora longicornis to the HAB species Alexandrium fundyense and examined effects on copepod survival, ingestion, egg production and swimming behaviour. A. fundyense was readily ingested by T...

High affinity agonist-binding (HAB) sites are formed from specific receptor interaction with guanine nucleotide-binding (Gi) proteins. To determine whether the release of endothelium-derived relaxing factor (EDRF) is regulated by specific receptor-Gi protein coupling, we treated bovine aortic endothelial cells with 100 ng/ml pertussis toxin (PTX) for 16 hours to effect receptor-Gi protein uncou...

MODIS medium-resolution (250and 500-m) bands were successfully used to detect and map the distribution of a harmful phytoplankton bloom (HAB) in the Paracas Bay, Peru, that caused economic losses estimated at about $28.5 million. A Red-Green-Blue combination of bands 1, 4 and 3 was used to visually distinguish the HAB while the turbidity index, a semi-quantitative measure of the amount of parti...

Current pharmacotherapy of anxiety disorders and depression mainly targets GABAA receptors and monoamines such as the serotonin and noradrenaline systems, respectively. They are effective, but an improvement of their therapeutic efficacy in regard of therapeutic onset, side effects and the number of treatment responders is desired. Here, we tested the sensitivity of a mouse line characterised b...

Epiboly, the spreading of the blastoderm over the large yolk cell, is the first morphogenetic movement of the teleost embryo. Examining this movement as a paradigm of vertebrate morphogenesis, we have focused on the epiboly arrest mutant half baked (hab), which segregates as a recessive lethal, including alleles expressing zygotic-maternal dominant (ZMD) effects. Here we show that hab is a muta...

Eco-HAB is an open source, RFID-based system for automated measurement and analysis of social preference and in-cohort sociability in mice. The system closely follows murine ethology. It requires no contact between a human experimenter and tested animals, overcoming the confounding factors that lead to irreproducible assessment of murine social behavior between laboratories. In Eco-HAB, group-h...

Center For The Treatment of Burns in Siemianowice Śląskie1 Dyrektor: dr n. med. M. nowak Technical-Humanistic Academy in Bielsko Biała. Faculty of Health Science. Faculty of Emergency Medicine2 Dziekan Wydziału: dr hab. M. Mikulska, prof. ATH Higher School of Applied Sciences in Ruda Śląska. Department of Health3 Dziekan Wydziału: doc. dr n. med. I. Caus-Woźniak Center of Polymer and Carbon Res...

Center For The Treatment of Burns in Siemianowice Śląskie1 Dyrektor: dr n. med. M. nowak Technical-Humanistic Academy in Bielsko Biała. Faculty of Health Science. Faculty of Emergency Medicine2 Dziekan Wydziału: dr hab. M. Mikulska, prof. ATH Higher School of Applied Sciences in Ruda Śląska. Department of Health3 Dziekan Wydziału: doc. dr n. med. I. Caus-Woźniak Center of Polymer and Carbon Res...