نتایج جستجو برای: haddock
تعداد نتایج: 402 فیلتر نتایج به سال:
During the development of selective peptides against highly homologous targets, a reliable tool is sought that can predict information on both mechanisms of binding and relative affinities. These tools must first be tested on known profiles before application on novel therapeutic candidates. We therefore present a comparative docking protocol in HADDOCK using critical motifs, and use it to "predic...
Our information-driven docking approach HADDOCK is a consistent top predictor and scorer since the start of its participation in the CAPRI community-wide experiment. This sustained performance is due, in part, to its ability to integrate experimental data and/or bioinformatics information into the modelling process, and also to the overall robustness of the scoring function used to assess and r...
Abstract Knowledge of recruitment and its variability in marine fish populations contributes to sustainable fisheries but a full understanding remains elusive. An earlier study showed that haddock (Melanogrammus aeglefinus) stocks exhibited consistently higher lower reproductive rates compared cod (Gadus morhua) the geographic regions where they co-occurred. Thus, may have resilience overexploi...
The toxicity resulting from exposure to oil droplets in marine fish embryos and larvae is still subject for debate. The most detailed studies have investigated the effects of water-dissolved components of crude oil in water accommodated fractions (WAFs) that lack bulk oil droplets. Although exposure to dissolved petroleum compounds alone is sufficient to cause the characteristic developmental t...
What licenses the use of a definite description? The formal and philosophical literature has approached this question in two ways. The uniqueness approach (Frege, 1892; Russell, 1905; Strawson, 1950) holds that we may use a definite determiner only if the property denoted by its complement holds of exactly one individual in some domain: Sentence (1) and (2) can only be true if there is exactly ...
A small assemblage of sieved fish remains was analysed from a medieval site on Lindisfarne. Haddock, cod and whiting were the most commonly consumed species, with small numbers of other taxa recovered, including herring and flatfish. Most were probably caught in local inshore or coastal waters, and most were only of moderate size. It is likely the remains include gutting and processing waste (i...
Insulin hormone is an important part of the endocrine system. It contains two polypeptide chains and plays a pivotal role in regulating carbohydrate metabolism. Insulin receptors (IR) located on cell surface interacts with insulin to control the intake of glucose. Although several studies have tried to clarify the interaction between insulin and its receptor, the mechanism of this interaction r...
Two studies examined the impact of subjective experiences on reports of attitude certainty, intensity, and importance. In Study 1, participants with moderate or extreme attitudes toward doctor-assisted suicide generated three (easy) or seven (hard) arguments that either supported or countered their opinion toward the issue prior to indicating the strength of their attitude. Participants with mo...
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