We studied the biogenesis of apolipoprotein B (apoB) in primary hepatocytes isolated from hamster liver, an animal model with striking resemblance to humans in lipoprotein metabolism. Hamster hepatocytes were found to assemble and secrete apoB-containing lipoproteins at a density of VLDL. Intracellular mechanisms of apoB biogenesis were investigated in both intact and permeabilized hamster hepa...

Farmland species face many threats, including habitat loss and malnutrition during key periods of their life cycle. This is aggravated in conventionally managed monocultures, leading to nutrient deficiencies that impair the survival reproduction farmland wildlife. For instance, protein wheat or vitamin B3 deficiency maize reduce by up 87% reproductive success critically endangered common hamste...

Prion diseases are progressive neurodegenerative disorders affecting humans and various mammals. The prominent neuropathological change in prion-affected brains is neuroinflammation, histopathologically characterized by reactive gliosis surrounding prion deposition. cause effect of these cellular responses still unclear. Here we investigate the impact innate immune on replication using vitro ce...

Transport infrastructures, such as highways, disrupt animal migrations and cause roadkill. To mitigate the latter problem, fences have been built but their effectiveness has rarely tested under controlled conditions. Here, we of most commonly used fence in France probably Europe (wire netting fence) to block animals. We wire fence, with without a structural modification (i.e. an overhang), thre...

The cortisonized adult hamster, the antithymocyte-treated newborn hamster, and the antithymocyte globulin-treated monkey were compared as in vivo test systems for the tumorigenic potential of cells. The newborn hamster and monkey systems were more consistent in allowing the expression of tumors than was the cortisonized hamster when each of three human tumor cell lines was assayed. Cells derive...

Transplantation of a human lymphoma to the cheek pouches of unconditioned, adult golden hamsters resulted in permanently transplantable tumors which grow progressively and kill their hosts. This tumor system, GW-478, has a hamster-specific láclate dehydrogenase isoenzyme mobility pattern and both human and hamster glucose 6-phosphate dehyrogenase enzyme profiles when propagated in the hamster ...

Why was it acceptable for me to utter this sentence, which contains the presuppositional expression my hamster? Presumably it’s because the sentence presupposes that I have a hamster; and a sentence with this presupposition is acceptable in any context like the one we’re in, where you and I come into the conversation sharing the belief that I have a hamster. It could also be that you didn’t kno...

The deacylation of tritium-labeled 12-O-tetradecanoylphorbol-13-acetate ([3H]TPA) and tritium-labeled phorbol-12,13-didecanoate ([3H]PDD) by hamster cells in culture and hamster skin in vivo was studied. Cell cultures of Syrian hamster embryo fibroblasts and preneoplastic or neoplastic derivatives of these cells deacylated [3H]TPA rapidly, and the major product ob served cochromatographed on si...

Chicken embryo lethal orphan (CELO) virus replication studies in adult hamster kidney and green monkey kidney cell cultures by means of infectivity, cytochemistry, and fluorescent-antibody techniques indicated that replication in hamster kidney cells was limited to the production of neoantigen. Production of virus in green monkey kidney cells was limited but appeared to exceed the production of...

A complementary DNA (cDNA) library was prepared from messenger RNA (mRNA) isolated from Syrian hamster islets. Bacterial colonies containing hamster preproinsulin cDNA were identified by cross-hybridization with the human preproinsulin gene. The sequences of two of these established the complete sequence of Syrian hamster preproinsulin mRNA and predicted the sequence of the protein. Hamster pre...