pleuropulmonary blastoma (ppb) is a rare, malignant intrathoracic tumor that occurs mostly in children before 5 years old. it consists about 15% of all primary pediatric pulmonary tumors and shows various mesenchymal components. its presentations are nonspecific and common symptoms include fever, cough, chest pain, respiratory distress, and pulmonary infection. ppb should be considered in the d...

using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...

background and aims. head and neck tumors are the most common complaints of people referring to different medical sections, especially in children. the aim of this study was to evaluate the prevalence of these tumors in children less than 12 years of age to provide a better perspective for future studies. materials and methods. all the files in department of pathology at tabriz pediatric hospit...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

BACKGROUND Primary malignant tumors of the hand, although unusual, may present varied and often complex clinical problems. The main treatment modality of skin cancer of the hand has changed. METHODS We retrospectively reviewed the medical records of 43 patients who underwent surgery for malignant skin tumors of the hand during an 18-year period, from September 1994 to February 2012. The chara...

The purpose of this study was to clarify clinical and radiographic features of bone changes associated with soft-tissue tumors of the hand. We reviewed clinical records and radiographs of 115 patients who had undergone operations for soft-tissue tumors or tumorous conditions of the hand. Bone changes were detected in the radiographs of 21 of the 115 patients. Giant cell tumor of tendon sheath w...

Soft tissue sarcomas of the hand and foot comprise a rare subgroup mesenchymal tumors with more favorable oncological prognosis. For this type tumors, several options surgical treatment exist depending on histological subtype, size local tumor advancement. Additionally, due to significant functional load distal parts limbs, techniques for these patients have specific characteristics. However, p...