The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives. Bismuth nitrate pentahydrate under microwave irradiation is proven to act as a very efficient catalyst for a one-pot, three-component synthesis of 1,4-dihydropyridines in excellent yields from diverse amines/...

We describe a modified method for determining triglycerides in serum, in which alumina is used to adsorb interfering substances, and the glycerol content of triglycerides is determined colorimetrically. In contrast to all previous Hantzsch condensation procedures in which periodate and acetylacetone are used, the working periodate and the working acetylacetone reagents are stable for at least s...

An efficient synthesis of polyhydroquinoline derivatives is achieved via Hantzsch condensation reaction between aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of catalytic amount of SFHS in ethanol. This method gives remarkable advantages such as shorter reaction time, simple workup procedure and good to excellent yields. Furthermore the catalyst can be recovered c...

An efficient synthesis of polyhydroquinoline derivatives is achieved via Hantzsch condensation reaction between aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of catalytic amount of SFHS in ethanol. This method gives remarkable advantages such as shorter reaction time, simple workup procedure and good to excellent yields. Furthermore the catalyst can be recovered c...

Results from an intercomparison of several currently used in-situ techniques for the measurement of atmospheric formaldehyde (CH2O) are presented. The measurements were carried out at Bresso, an urban site in the periphery of Milan (Italy) as part of the FORMAT-I field campaign. Eight instruments were employed by six independent research groups using four different techniques: Differential Opti...

The amino acid proline catalyzed the three- and five-component cascade olefination-Diels-Alder-epimerization and olefination-Diels-Alder-epimerization-olefination-hydrogenation reactions of readily available precursors enones 1a-i, arylaldehydes 2a-k, alkyl cyanoacetates 3a-e and Hantzsch ester 9 to furnish highly substituted prochiral 1-cyano-4-oxo-2,6-diaryl-cyclohexanecarboxylic acid alkyl e...

The title mol-ecule, C(17)H(19)NO(5), was prepared by a Hantzsch dihydro-pyridine synthesis from 4-hy-droxy-benzaldehyde, methyl acetoacetate and NH(4)HCO(3). In the mol-ecular structure of the title compound, the dihydro-pyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 80.8 (2)° with the aromatic six-membered ring. The packing i...

The synthesis of a novel dihydropyridine derivatives bearing dimedone as an excellent precursor has been achieved by applying three component Hantzsch condensation. The newly synthesized compounds were characterized by IR, NMR, Mass spectra and also by C, H, N analyses. All synthesized compounds undergo docking studies and biological screening for antimicrobial activity against Gram-positive ba...