Androgen receptor (hAR) regulates transcription of target genes in a ligand-dependent manner and recruits a number of co-activators for the ligand-induced transactivation via the N-terminal, activation function-1 (AF-1), and C-terminal, AF-2, transactivation domains. But the co-regulator functions on each of AR domains have not yet been fully understood. We have established a Drosophila transge...

I dette foredraget vil vi presentere et prosjekt som nettopp har kommet i gang, og som har fått NOK 1 000 000 fra NorFA til et nordisk nettverk. Prosjektet har to siktemål som henger nøye sammen. Det ene er å bygge nettverk mellom fire forskningsog utviklingsmiljøer ved UiO (Tekstlaboratoriet), UiB (HIT-senteret), GU (Språkdata) og CST. Det andre er praktisk: å utvikle en automatisk navnegjenkj...

Hirshfeld atom refinement (HAR) is a novel X-ray structure refinement technique that employs aspherical atomic scattering factors obtained from stockholder partitioning of a theoretically determined tailor-made static electron density. HAR overcomes many of the known limitations of independent atom modelling (IAM), such as too short element-hydrogen distances, r(X-H), or too large atomic displa...

Prey selection was assumed to be a vital strategy to maximize the fitness of predators. Visual cues are important for predators to locate a prey, and several species of lady beetles have been reported to prefer the red morph pea aphid Acyrthosiphon pisum rather than the green morph in empty containers with different colors. However, the preference of a predator on the red and green color morphs...

Baka is a platelet alloantigen whose putative allele, Bakb, has not been identified previously. By using a serum, "Har," obtained from a patient with posttransfusion purpura, we describe the platelet alloantigen Bakb. The Har serum reacted with an NP-40-extractable platelet membrane protein of 142 kd with mobility similar to platelet glycoprotein IIb alpha. We found that the antigen recognized ...

Harmine is a beta-carboline alkaloid found in medicinal plant PeganumHarmala, which has served as a folk anticancer medicine. However, clinical applications of harmine were limited by its low pharmacological effects and noticeable neurotoxicity. In this study, we modified harmine to increase the therapeutic efficacy and to decrease the systemic toxicity. Specifically, two tumor targeting harmin...

During the last 5 years, research on Human Activity Recognition (HAR) has reported on systems showing good overall recognition performance. As a consequence, HAR has been considered as a potential technology for ehealth systems. Here, we propose a machine learning based HAR classifier. We also provide a full experimental description that contains the HAR wearable devices setup and a public doma...

The least squares method has been applied to estimate parameters in an aerodynamic model of a simulated aircraft, using data that can be expected to available from sensors on an Unmanned Aerial Vehicle. A combination of two non-linear state observers have been implemented to estimate wind data such as angle of attack, sideslip and dynamic pressure. Simulations have confirmed that the observers ...

Grass pea (Lathyrus sativus L.) has great agronomic potential as grain and forage legume, and presently is considered as a model crop for sustainable agriculture. However, the development into an important food legume has been hindered by the presence of the neurotoxic amino acid β-N-Oxalyl-α, β-diaminopropionic acid (β-ODAP). Recent studies reported that homoarginine (Har) can counteract this ...

Many Human Activity Recognition (HAR) systems are able to detect sequential executed Activity of Daily Living (ADL). However, a person is capable of doing two things in parallel or pausing one ADL and finishing it later. Thus, a HAR system must be capable of remembering and deciding which ADL is completed and which might be continued after the current ADL. We address this case by combining a st...