AIMS Hawthorn's efficacy when added to contemporary evidence-based heart failure therapy is unknown. We aimed to determine whether hawthorn increases submaximal exercise capacity when added to standard medical therapy. METHODS AND RESULTS We performed a randomized, double-blind, placebo-controlled trial in 120 ambulatory patients aged > or = 18 years with New York Heart Association (NYHA) cla...

From the flowers of meadowsweet and inflorescence of hawthorn the whole set of phenolic acids and flavonoids was analysed by TLC. Phenolic compounds were determined both as free ones and those liberated by hydrolysis. Moreover, ethyl ether and ethyl acetate extracts obtained from the analysed plants before and after alkaline and enzymatic hydrolyses were evaporated under reduced pressure and re...

Objective: To study the preparation process of anti-aging healthy beverage. Methods: L9 (34) was used to identify, weigh and pretreat raw materials, optimize and make an orthogonal experiment with as reference, screen out the optimal formula of beverage blending in accordance with sensory score. Results: The best formula of anti-aging healthy beverage with compound hawthorn and Astragalus membr...

The two acknowledged vectors of ‘Candidatus Phytoplasma mali’ in north-western Italy, the psyllid Cacopsylla melanoneura and the leafhopper Fieberiella florii, have been compared to highlight their role in the apple proliferation epidemiology in relation to their infectivity, transmission efficiency and permanence in apple orchards and in wild vegetation, predominantly hawthorn formations. The ...

Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs has been isolated from natural sources, many based on their use in traditional medicine.Plant extracts are attractive sources of new drugs and have been shown to produce promising results in the treatment of various diseases.Crataegus oxyacantha Linn., commonly known as Hawthorn, is one ...

STUDY OBJECTIVE To determine the effects of hawthorn (Crataegus oxycantha) on left ventricular remodeling and function in pressure overload-induced heart failure in an animal model. DESIGN Randomized, parallel, dose-ranging animal study. SETTING University research facility. ANIMALS Seventy-four male Sprague-Dawley rats; 44 were included in the final analysis. INTERVENTION Rats underwen...

The hawthorn fruit (Crataegus pinnatifida Bunge var. typica Schneider) is used as a traditional medicine in Korea. The objective of this study was to understand the mechanisms of the anti-inflammatory effects of the water fractionated portion of hawthorn fruit on a lipopolysaccharide (LPS)-stimulated RAW 264.7 cellular model. The level of nitric oxide (NO) production in the water fraction and L...

Crataegus monogyna, commonly known as hawthorn, is notorious for having different ethnopharmacological applications. The antioxidant activity of methanolic extracts from its flowers and fruits in several stages of development was formerly reported by us. Therefore it is believable that the extracts of its botanical parts might have great potential to be incorporated in innovative pharmaceutical...

The influence of vegetal extracts derived from red grape, blueberry fruits and hawthorn leaves on Zea mays L. plant growth and the activity of phenylalanine ammonia-lyase (PAL), a key enzyme of the phenylpropanoid pathway, was investigated in laboratory experiments. The extracts were characterized using FT-IR and Raman spectroscopies in order to obtain a pattern of the main functional groups. I...