Healing is an intrinsic ability in the incredibly biodiverse populations of the plant and animal kingdoms created through evolution. Plants and animals approach healing in similar ways but with unique pathways, such as damage containment in plants or clotting in animals. After analyzing the examples of healing and defense mechanisms found in living nature, eight prevalent mechanisms were identi...

The relationship between host nutrition and wound healing has been the subject of study and experimentation for centuries. Despite the many years of study and a substantial knowledge base of the specific processes and factors involved, wound healing remains enigmatic. There is still much to learn about the wound-specific nutritional interventions that are available to improve wound healing. Nut...

Enterocutaneous fistula is a challenging clinical condition with serious complications and considerable morbidity and mortality. Early nutritional support has been found to decrease these complications and to improve the clinical outcome. Location of the fistula and physiological status affect the nutrition management plan in terms of feeding route, calories, and protein requirements. This stud...

The aim of this study was to investigate the relationship between microstructural parameters, material distribution, and mechanical properties of sheep tibia at the apparent and tissue levels during the fracture healing process. Eighteen sheep underwent tibial osteotomy and were sacrificed at 4, 8, and 12 weeks. Radiographs and micro-computed tomography (micro-CT) scanning were taken for micros...

In the movement to improve the health of patients with multiple chronic conditions and vulnerabilities, while reducing the need for hospitalizations, care management programs have garnered wide attention and support. The qualitative data presented in this paper sheds new light on key components of successful chronic care management programs. By going beyond a task- and temporal-based framework,...

3 Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA The clinical role of prostaglandins in fracture healing has yet to be fully elucidated. Data from animal models have shown that some nonsteroidal anti-inflammatory medications (NSAIDs) inhibit fracture healing. However, a clear clinical association between prostaglandin inhibition and delayed fracture healing has not been ...

The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (n = 52) and macerated wounds (n = 18). Each ...